123992-15-4

Upstream product

• 109-80-8 1.3-propanedithiol 
• 123992-14-3 <2S-<2α(2R*,3S*,4R*),3β,5β,6β>>-(1,1-Dimethylethyl)<<2-methyl-3-(phenylmethoxy)-4-pentyl>oxy>diphenylsilane (Pyran 14) 
• 124095-53-0 Methyl 2,4-Dideoxy-2,4-dimethyl-α-L-xylopyranoside (Pyran 6) 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 123992-10-9 (2S,3R,4S)-3-Benzyloxy-5-(tert-butyl-diphenyl-silanyloxy)-2,4-dimethyl-pentanal 
• 123992-13-2 <2S-<2α(2R*,3S*,4R*),3β,6β>>-<<4-<3,6-Dihydro-3,5-dimethyl-6-(1-methylethoxy)-2H-pyran-2-yl>-2-methyl-3-(phenylmethoxy)pentyl>oxy>(1,1-dimethylethyl)diphenylsilane (Pyran 13) 
• 123992-12-1 1,5-Anhydro-2,4,6,8-tetradeoxy-9-O-<(1,1-dimethylethyl)-diphenylsilyl>-2,4,6,8-tetramethyl-7-O-(phenylmethyl)-L-threo-L-galacto-non-1-enitol (Pyran 12) 
• 123992-11-0 1,5-Anhydro-2,4,6,8-tetradeoxy-9-O-<(1,1-dimethylethyl)-diphenylsilyl>-2,4,6,8-tetramethyl-7-O-(phenylmethyl)-L-glycero-D-gulo-non-1-en-3-ulose (Pyrone 11) 
• 123992-09-6 2,4-Dideoxy-5-O-<(1,1-dimethylethyl)diphenylsilyl>-2,4-dimethyl-3-O-(phenylmethyl)-L-xylose, Cyclic 1,3-Propanediyl Mercaptal (Dithiane 9) 
• 123992-08-5 2,4-Dideoxy-5-O-<(1,1-dimethylethyl)diphenylsolyl>-2,4-dimethyl-L-xylose, Cyclic 1,3-Propanediyl Mercaptal (Alcohol 8) 
• 98703-75-4 (E,Z)-3-<(tert-butyldimethylsilyl)oxy>-1-methoxy-2-methyl-1,3-pentadiene 
• 123992-07-4 2,4-Dideoxy-2,4-dimethyl-L-xylose Cyclic 1,3-Propanediyl Mercaptal (Diol 7) 
• 123992-05-2 cis/trans-(+/-)-5,6-Dihydro-2-methoxy-3,5-dimethyl-2H-pyran (Pyran 5) 
• 36019-62-2 2,3-Dihydro-3,5-dimethyl-4H-pyran-4-one (Pyrone 4) 

Downstream Products

• 123992-16-5 <2S-(2R*,3S*,4S*,5R*,6R*,8S*)>-(1,1-Dimethylethyl)-<<8-(1,3-dithian-2-yl)-2,4,6-trimethyl-3,5-bis(phenylmethoxy)nonyl>oxy>diphenylsilane (Dithiane 16) 
• 123992-17-6 (2R,4S,5S,6R,7R,8S)-5,7-Bis-benzyloxy-9-(tert-butyl-diphenyl-silanyloxy)-2,4,6,8-tetramethyl-nonanal 
• 123992-30-3 <2S-(2R*,3S*,4S*,5R*,6R*,8S*,9R+,10R*,11R*,12R*,13S*)>-2,4,6,8,10,12-Hexamethyl-3,5,9,11-tetrakis(phenylmethoxy)-1,13-pentadecanediol (Diol 40) 
• 123992-32-5 (3R,4S,5R,6S,7S,9R,10S,11S,12S,13S,14R)-4,6,10,12-Tetrakis-benzyloxy-14-ethyl-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one 
• 123992-19-8 <2S-<2α(1S*,3R*,4R*,5S*,6S*,7R*),3β,4α>>-2-<8-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-1,3,5,7-tetramethyl-4,6-bis-(phenylmethoxy)octyl>-3,4-dihydro-3,5-dimethyl-4H-pyran-4-ol (Pyran 20) 
• 123992-20-1 <2R-<2α,5α,6β(1R*,3S*,4S*,5R*,5R*,7S*)>>-2-<<6-<8-<<(1,1-Dimethylethyl)diphenylsilyl>oxy >-1,3,5,7-tetramethyl-4,6-bis(phenylmethoxy)octyl>-5,6-dihydro-3,5-dimethyl-2H-pyran-2-yl>oxy>ethanol (Allylic Alcohol 26) 
• 123992-21-2 <4R-(2Z,4R*,5S*,6R*,8S*,9S*,10R*,11R*,12S*)>-13-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-2,4,6,8,10,12-hexamethyl-3,5-bis(phenylmethoxy)-9-hydroxy-2-tridecenyl 2,2-Dimethylpropanoate (Allylic Ester 27) 
• 123992-23-4 <4R-(2Z,4R*,5S*,6R*,8S*,9S*,10R*,11R*,12S*)>-13-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-2,4,6,8,10,12-hexamethyl-5,9,11-tris(phenylmethoxy)-2-tridecen-1-ol (Allylic Alcohol 29) 
• 123992-25-6 <2S-(2R*,3R*,4S*,5R*,6S*,8R*,9R*,10S*,11S*,12R*)>-13-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-2,4,6,8,10,12-hexamethyl-5,9,11-tris(phenylmethoxy)-1,3-tridecanediol (Diol 34) 
• 123992-28-9 (2R,3R,4S,5S,6R,8S,9S,10R,11R,12S)-3,5,9,11-Tetrakis-benzyloxy-13-(tert-butyl-diphenyl-silanyloxy)-2,4,6,8,10,12-hexamethyl-tridecanal 
• 123992-27-8 <2S-(2R*,3R*,4R*,5R*,6S*,8R*,9R+,10S*,11S*,12R*)>-13-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-2,4,6,8,10,12-hexamethyl-3,5,9,11-tetrakis(phenylmethoxy)-1-tridecanol (Alcohol 36) 
• 123992-29-0 <3R-(3R*,4S*,5S*,6S*,8R*,10S*,11S*,12R*,13R*,14S*)>-153-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-4,6,8,10,12,14-hexamethyl-5,7,11,13-tetrakis(phenylmethoxy)-3-pentadecanol (Alcohol 2) 
• 123992-33-6 <5R-(5R*,6R*,7R*,8S*,9S*,10R*,12S*,13S*,14R*,15R*,16S*)>-5-Ethyl-2,2,3,3,6,8,10,12,14,16,20,20-dodecamethyl-19,19-diphenyl-7,9,13,15-tetrakis(phenylmethoxy)-4,18-dioxa-3,19-disilaheneicosane (Protected Hexaol 41) 
• 123992-18-7 <2S-<2α(1S*,3R*,4R*,5S*,6S*,7R*),3β>>-2-<8-<<(1,1-Dimethylethyl)diphenylsilyl>oxy>-1,3,5,7-tetramethyl-4,6-bis(phenylmethoxy)octyl>-2,3-dihydro-3,5-dimethyl-4H-pyran-4-one (Pyrone 18) 

Relevant academic research and scientific papers

Development of a fully synthetic stereoselective route to 6-Deoxyerythronolide B by reiterative applications of the Lewis acid catalyzed diene aldehyde cyclocondensation reaction: A remarkable instance of diastereofacial selectivity

The synthesis of racemic 2, which contains the relative stereochemistry appropriate to a synthesis of (9S)-dihydro-6-deoxyerythronolide B (see compound 38), is described. The synthesis features three Lewis acid catalyzed diene aldehyde cyclocondensation r