1239968-06-9Relevant articles and documents
Perylenyltriazoles inhibit reproduction of enveloped viruses
Aralov, Andrey V.,Proskurin, Gleb V.,Orlov, Alexey A.,Kozlovskaya, Liubov I.,Chistov, Alexey A.,Kutyakov, Sergey V.,Karganova, Galina G.,Palyulin, Vladimir A.,Osolodkin, Dmitry I.,Korshun, Vladimir A.
, p. 293 - 299 (2017)
1-Substituted 4-perylen-2(3)-yl-1,2,3-triazoles, easily accessible by ‘click’ reaction and combining in one molecule a polyaromatic unit and a nitrogen heterocycle, were found to strongly inhibit the reproduction of enveloped viruses. 5-[4-(Perylen-3-yl)-
Highly efficient and facile synthesis of 5-azido-2'-deoxyuridine
Gourdain, Stephanie,Petermann, Christian,Harakat, Dominique,Clivio, Pascale
, p. 542 - 546 (2010)
Previously reported syntheses of the photoaffinity label 5-azido-2'-deoxyuridine are rather inefficient and involve the tedious preparation of a 5-nitro intermediate. To overcome these inconveniences, we have developed a new approach from the commercially available 5-bromo-2'- deoxyuridine nucleoside. Our synthetic route makes use of a benzylamination reduction sequence. Using this strategy, the 5-azido-2'-deoxyuridine photolabel is prepared in three steps and quantitative yields. Copyright Taylor and Francis Group, LLC.