124015-87-8

Upstream product

• 1193-55-1 2-methylcyclohexane-1,3-dione 
• 57-14-7 N,N-Dimethylhydrazine 
• 504-02-9 1,3-cylohexanedione 
• 69948-55-6 3-(2,2-dimethylhydrazino)cyclohex-2-en-1-one 
• 74-88-4 methyl iodide 

Downstream Products

• 124015-84-5 4-Benzyl-2-methyl-cyclohexane-1,3-dione 
• 20990-14-1 2,4-dimethyl-1,3-cyclohexanedione 
• 124015-82-3 3-(N',N'-Dimethyl-hydrazino)-2,4-dimethyl-cyclohex-2-enone 
• 124948-38-5 3,7-dioxo-6-methyl-8-(2-oxo-but-4-yl)-bicyclo<4.4.0>decen-1 
• 124015-83-4 4-Benzyl-3-(N',N'-dimethyl-hydrazino)-2-methyl-cyclohex-2-enone 
• 127311-61-9 2-benzyl-2-methyl-cyclohexane-1,3-dione 
• 32561-55-0 2-methyl-2-(prop-2-yn-1-yl)cyclohexane-1,3-dione 
• 25112-82-7 2-ethyl-2-methyl-cyclohexane-1,3-dione 
• 562-13-0 2,2-dimethyl-1,3-cyclohexanedione 

Relevant academic research and scientific papers

Regioselective alkylations of cyclic 1,3-diketones via metalated dimethylhydrazones

Cyclic 1,3- diketones 1 are transformed into their 2,2-dimethylhydrazones 2, which can be alkylated regioselectively at different positions after mono-, di-, tri-, and tetrametalation. Monometalated C-2 unsubstituted hydrazones afford C-2 and N- alkylation, monometalated C-2 substituted hydrazones afford only C-2 alkylation.The regioselectivity of the alkylation of the polymetalated hydrazones follows Hauser's rule according to the sequence: NH- > C-4 Ha > C-5 > C-4 Hb. Hydrolysis of the product hydrazones 3-5 afforded mono- and polyalkylated 1,3- diketones 7 in good yields.

Synthesis of Bicyclic and Tricyclic Enones via Regioselektive Dialkylation of Cyclic 1,3-Diketone-dimethylhydrazones with 4-Chlorobutane-2-one

An efficient, regioselective synthesis of substituted bicyclo nonenes and decenes of type (4a,b) and the tricyclic tetradecadiene (5) is described.The key step is the regioselective dialkylation of cyclic 1,3-diketone-dimethylhydrazones (1a-e) with 4-chlo