124097-84-3

Upstream product

• 7429-44-9 2-methoxycyclohexanone 
• 124034-83-9 (2S)-2-methoxymethyl-1-[2-(pyridin-3-yl)-cyclohexylideneamino]pyrrolidine 
• 148322-26-3 (+)-2-methoxy-1-(pyrid-3-yl)cyclohexanol 
• 124034-66-8 2-(pyridin-3-yl)-cyclohexanone 
• 626-55-1 3-Bromopyridine 
• 133667-53-5 (S)-2-[(E)-(R)-1-Phenyl-ethylimino]-1-pyridin-3-yl-cyclohexanecarbothioic acid methylamide 
• 124034-18-0 (S)-2-[(E)-(S)-2-Methoxymethyl-pyrrolidin-1-ylimino]-1-pyridin-3-yl-cyclohexanecarbothioic acid methylamide 
• 145931-38-0 ((R)-1-Phenyl-ethyl)-[2-pyridin-3-yl-cyclohex-(E)-ylidene]-amine 

Downstream Products

• 133321-21-8 [1S,2R]-trans-2-hydroxy-N-methyl-1-(pyridin-3-yl)cyclohexanecarbothioamide 
• 133320-02-2 [1S,2R]-trans-2-Benzoyloxy-N-methyl-1-(pyrid-3-yl)cyclohexanecarbothioamide 
• 145931-39-1 C₂₇H₂₆N₂O₃S 

Relevant academic research and scientific papers

Thioformamide derivatives

Thioformamide derivatives of the formula (I) STR1 wherein R represents an alkyl group; A represents either: (1) a phenyl group which is optionally substituted; or (2) heteroaromatic group (e.g. pyrid-3-yl, quinolin-3-yl); Y represents: an ethylene or methylene group or a direct bond; and B represents either: a) a phenyl, pyridyl, furyl or thienyl group, each of which may be optionally substituted, or b) a straight- or branched-chain alkyl, alkenyl, or cycloalkyl group, each of which may be optionally substituted. These compounds may be formulated into pharmaceutical preparations and have utility in the treatment of disorders associated with smooth muscle contraction.

The synthesis of RP 66471. A potent potassium channel opener

The potent, homochiral, potassium channel opener, RP 66471, has been synthesised and shown to possess the (1R,2S) configuration.