124034-66-8Relevant articles and documents
Palladium-Catalyzed Direct α-C(sp3) Heteroarylation of Ketones under Microwave Irradiation
Quillen, Andrew,Nguyen, Quynh,Neiser, Matthew,Lindsay, Kara,Rosen, Alexander,Ramirez, Stephen,Costan, Stefana,Johnson, Nathan,Do, Thuy Donna,Rodriguez, Oscar,Rivera, Diego,Atesin, Abdurrahman,Ate?in, Tülay Aygan,Ma, Lili
, p. 7652 - 7663 (2019)
Heteroaryl compounds are valuable building blocks in medicinal chemistry and chemical industry. A palladium-catalyzed direct α-C(sp3) heteroarylation of ketones under microwave irradiation is developed and reported in this study. Under optimized condition
Thioformamide derivatives
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, (2008/06/13)
Thioformamide compounds of formula (I) are disclosed in which R is alkyl, Y is methylene, ethylene or a direct bond, A is optionally substituted phenyl or pyridyl, R1 is hydrogen and R2 is N-alkylsulphonyl-, N-phenylsulphonyl-N'-alky
Derivatives of thioformamide
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, (2008/06/13)
Therapeutically useful thioformamide derivatives of the formula: STR1 wherein R represents alkyl, Het represents pyrid-3-yl, isoquinolin-4-yl, tetrahydroquinolin-3-yl, quinolin-3-yl, pyridazin-4-yl, pyrimid-5-yl, thiazol-5-yl, thieno[2,3-b]-pyridin-5-yl, pyrazin-2-yl, indol-3-yl and thieno[3,2-b]-pyridin-6-yl, Y represents ethylene, methylene or a valency bond, and X represents carbonyl, hydroxymethylene, >C=NOR1, >C=NN(R1)2 or >C=NN(R1)CON(R1)2 in which R1 represents hydrogen or optionally substituted alkyl, benzyl, phenethyl, 1-naphthylmethyl, 2-naphthylmethyl or pyrid-3-ylmethyl, or two R1 substituents on the same nitrogen atom may together form an optionally substituted alkylene radical chain and salts thereof, processes for their preparation and compositions containing them are described.