124145-27-3Relevant academic research and scientific papers
Multiple Aryne Insertions into Oxindoles: Synthesis of Bioactive 3,3-Diarylated Oxindoles and Dibenzo[b,e]azepin-6-ones
Samineni, Ramesh,Bandi, Chandramohan Reddy C.,Srihari, Pabbaraja,Mehta, Goverdhan
supporting information, p. 6184 - 6187 (2016/12/09)
An aryne insertion cascade reaction on oxindoles has been observed and constitutes a convenient one pot preparation of bioactive di- and triarylated oxindoles in good yields under mild conditions. A temperature controlled reaction switch enables ready access to dibenzo[b,e]azepin-6-one derivatives employing the same reaction regime. This tactic has been extended to a short synthesis of potent antiulcer agent darenzepine.
Transition metal and base-free synthesis of 3,3-diaryl-2-oxindoles from 2,2,N-triarylacetamides
Lim, Jin Woo,Kim, Ko Hoon,Moon, Hye Ran,Kim, Jae Nyoung
supporting information, p. 784 - 787 (2016/02/03)
A transition metal and base-free synthesis of 3,3-diaryl-2-oxindoles has been developed from 2,2,N-triarylacetamides in the presence of montmorillonite K-10 in 1,2-dichlorobenzene under O2 balloon atmosphere.
α-Arylation of oxindoles using recyclable metal oxide ferrite nanoparticles: Comparison between the catalytic activities of nickel, cobalt and copper ferrite nanoparticles
Moghaddam, Firouz Matloubi,Tavakoli, Ghazal,Latifi, Fatemeh,Saeednia, Borna
, p. 37 - 41 (2015/12/24)
Three different spinel metal oxide catalytic systems including NiFe2O4, CuFe2O4 and CoFe2O4 were synthesized using co-precipitation technique and their catalytic activities were compared to
3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION
-
Page/Page column 32, (2008/06/13)
Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, and/or (4) disorders associated with viral infections, using 3-(5-tert-butyl-2-hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol-2-one and/or its derivatives are described.
Preparation of 3,3-Diaryloxindoles by superacid-induced condensations of isatins and aromatics with a combinatorial approach
Klumpp, Douglas A.,Yeung, Ka Yeun,Prakash, G.K. Surya,Olah, George A.
, p. 4481 - 4484 (2007/10/03)
3,3-Diaryloxidoles are prepared in high yields (62-99%) by reaction of isatin or substituted isatins with aromatics in triflic acid. The reaction shows a significant dependence on acid strength which suggests the formation of diprotonated, superelectrophi
