1241794-93-3

Basic information

• Product Name: tert-butyl methyl (R)-2-(benzoyloxy)-2-benzylmalonate
• Synonyms: tert-butyl methyl (R)-2-(benzoyloxy)-2-benzylmalonate
• CAS NO: 1241794-93-3
• Molecular Weight: 384.429
• Mol File: 1241794-93-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: tert-butyl methyl (R)-2-(benzoyloxy)-2-benzylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl methyl (R)-2-(benzoyloxy)-2-benzylmalonate(1241794-93-3)
• EPA Substance Registry System: tert-butyl methyl (R)-2-(benzoyloxy)-2-benzylmalonate(1241794-93-3)

Safety Data

• Hazardous Substances Data: 1241794-93-3(Hazardous Substances Data)

Upstream product

• 4491-46-7 2-benzyl-malonic acid tert-butyl ester methyl ester 
• 94-36-0 dibenzoyl peroxide 
• 100-39-0 benzyl bromide 
• 42726-73-8 methyl t-butyl malonate 
• 1241794-80-8 tert-butyl methyl 2-(benzoyloxy)malonate 

Relevant articles and documents

Enantioselective α-Benzoyloxylation of Malonic Diesters by Phase-Transfer Catalysis

A highly enantioselective α-benzoyloxylation of malonic diester has been achieved by phase-transfer catalysis. The reaction of α-monosubstituted tert-butyl methyl malonate with benzoyl peroxide in the presence of aqueous KOH and N-(9-anthracenylmethyl)cinchoninium chloride afforded the corresponding α,α-disubstituted products in generally excellent chemical yields (up to 99% yield) with high enantioselectivities (up to 96% ee). In addition, the utility of this methodology was exhibited by the synthesis of a mineralocorticoid receptor antagonist.