1242002-08-9

Upstream product

• 1052713-78-6 tert-butyl 3-hydroxy-3-(trifluoromethyl)piperidine-1-carboxylate 
• 67-56-1 methanol 
• 156722-68-8 CF₃O₃S^(1-)*C₁₂H₁₆NO⁽¹⁺⁾ 
• 81290-20-2 (trifluoromethyl)trimethylsilane 

Downstream Products

• 1242002-09-0 1-benzyl-2-trifluoromethylpyrrolidine 
• 1242002-11-4 1-benzyl-2-phenacyl-2-trifluoromethylpyrrolidine 
• 1242002-12-5 methyl 2-(1-benzyl-2-trifluoromethylpyrrolidin-2-yl)-2-methylpropionate 
• 1242002-13-6 1-benzyl-2-trifluoromethylpyrrolidine-2-carbonitrile 
• 1242002-10-3 2-allyl-1-benzyl-2-trifluoromethylpyrrolidine 

Relevant academic research and scientific papers

Ring Contraction of 3-Hydroxy-3-(trifluoromethyl)piperidines: Synthesis of 2-Substituted 2-(Trifluoromethyl)pyrrolidines

A ring contraction of 3-hydroxy-3-(trifluoromethyl)piperidines was achieved via an aziridinium intermediate. This contraction facilitates the synthesis of a series of 2-substituted 2-(trifluoromethyl)pyrrolidines incorporating a quaternary center at the C2 position. Contractual obligations: A ring contraction of 3-hydroxy-3-(trifluoromethyl)piperidines was achieved via an aziridinium intermediate. This contraction facilitates the synthesis of a series of 2-substituted 2-(trifluoromethyl)pyrrolidines incorporating a quaternary center at the C2 position.