124267-23-8

Upstream product

• 78999-24-3 5-benzyloxy-1-pentanal 
• 100-39-0 benzyl bromide 
• 124-38-9 carbon dioxide 
• 2009-83-8 6-chloro-1-hexanol 
• 100-44-7 benzyl chloride 
• 629-30-1 1,7-heptandiol 
• 141943-06-8 1,7-heptanediol monobenzyl ether 
• 871732-99-9 7-benzyloxy-hept-2-enoic acid ethyl ester 
• 4541-15-5 5-(benzyloxy)-1-pentanol 
• 111-29-5 1 ,5-pentanediol 
• 871732-89-7 7-benzyloxy-heptanoic acid methyl ester 

Downstream Products

• 169269-83-4 7-Benzyloxy-heptanoyl chloride 
• 871732-92-2 (2R)-7-benzyloxy-2-methyl-heptanoic acid methyl ester 
• 871733-01-6 (2R)-7-benzyloxy-2-methyl-heptanoic acid 
• 871732-90-0 (4R)-3-(7-benzyloxy-1-oxoheptyl)-4-benzyl-2-oxazolidinone 
• 871732-91-1 [(2'R),4R]-3-(7-benzyloxy-2-methyl-1-oxoheptyl)-4-benzyl-2-oxazolidinone 
• 871732-95-5 (S)-2-[Methyl-((S)-3-methyl-2-{methyl-[(S)-3-methyl-2-(methyl-{(S)-3-methyl-2-[methyl-((R)-2-methyl-oct-7-ynoyl)-amino]-butyryl}-amino)-butyryl]-amino}-butyryl)-amino]-3-phenyl-propionic acid tert-butyl ester 
• 871733-05-0 (S)-2-[Methyl-((S)-3-methyl-2-{methyl-[(S)-3-methyl-2-(methyl-{(S)-3-methyl-2-[methyl-((S)-2-methyl-oct-7-ynoyl)-amino]-butyryl}-amino)-butyryl]-amino}-butyryl)-amino]-3-phenyl-propionic acid tert-butyl ester 
• 169269-84-5 (4S)-3-(7-benzyloxy-1-oxoheptyl)-4-benzyl-2-oxazolidinone 
• 169269-88-9 (R)-2-(5-Benzyloxy-pentyl)-succinic acid 4-tert-butyl ester 
• 169269-93-6 (R)-8-Hydroxy-3-((S)-1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-octanoic acid tert-butyl ester 
• 1027325-77-4 (R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamoyl)-8-phenoxy-octanoic acid 
• 169269-92-5 (R)-8-Benzyloxy-3-((S)-1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-octanoic acid 
• 169269-90-3 (R)-8-Benzyloxy-3-((S)-1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-octanoic acid tert-butyl ester 
• 169269-97-0 (R)-3-((S)-1-Methylcarbamoyl-2-phenyl-ethylcarbamoyl)-8-phenoxy-octanoic acid tert-butyl ester 

Relevant academic research and scientific papers

Enhanced Spacer Length between Mannose Mimicking Shikimoyl and Quinoyl Headgroups and Hydrophobic Region of Cationic Amphiphile Increases Efficiency of Dendritic Cell Based DNA Vaccination: A Structure-Activity Investigation

In the field of dendritic cell based genetic immunization, previously we showed that liposomes of cationic amphiphiles containing mannose-mimicking shikimoyl headgroup are promising DNA vaccine carriers for dendritic cell (DC) transfection. The present structure-activity study reports on the influence of spacer length (between mannose-mimicking headgroups and quaternary nitrogen centers) in modulating the DC-transfection efficiencies. Further, we report on the anti-melanoma immune response inducing properties of the promising cationic amphiphiles in syngeneic C57BL/6J mice under prophylactic settings.

Ni-Catalyzed Carboxylation of Unactivated Alkyl Chlorides with CO2

A catalytic carboxylation of unactivated primary, secondary, and tertiary alkyl chlorides with CO2 at atmospheric pressure is described. This protocol represents the first intermolecular cross-electrophile coupling of unactivated alkyl chlorides, thus leading to new knowledge in the cross-coupling arena.

Nickel-catalyzed carboxylation of organozinc reagents with CO2

(Chemical Equation Presented) An efficient nickel catalyst system for the carboxylation of organozinc reagents with CO2 under very mild conditions has been developed. The catalyst system complements the conventional methods and enables the dire

The total synthesis and reassignment of stereochemistry of dragonamide

The first total synthesis of dragonamide is reported. The synthesis has led to a reassignment of the configuration at the stereogenic centre on the alkyne-bearing fragment of the molecule.

Inhibition of matrix metalloproteinases by hydroxamates containing heteroatom-based modifications of the P1' group

In this study, structure-based drug design of matrix metalloproteinase inhibitors [human fibroblast collagenase (HFC), human fibroblast stromelysin (HFS), and human neutrophil collagenase (HNC)] was utilized in the development of potent hydroxamates which