124276-67-1

Basic information

• Product Name: 1-(4-BROMOPHENYL)CYCLOPROPANECARBONITRILE, 97
• Synonyms: 1-(4-BROMOPHENYL)CYCLOPROPANECARBONITRILE, 97;1-(4-Bromophenyl)-1-cyanocyclopropane;1-(4-Bromophenyl)cyclopropane-1-carbonitrile;1-(4-Bromophenyl)-1-cyclopropanecarbonitrile;Cyclopropanecarbonitrile, 1-(4-bromophenyl)-
• CAS NO: 124276-67-1
• Molecular Formula: C₁₀H₈BrN
• Molecular Weight: 222.084
• Mol File: 124276-67-1.mol
• Article Data: 37

Chemical Properties

• Melting Point: 84℃
• Boiling Point: 321.4°Cat760mmHg
• Flash Point: 148.2°C
• Appearance: /
• Density: 1.53
• Vapor Pressure: 0.000159mmHg at 25°C
• Refractive Index: 1.601
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(4-BROMOPHENYL)CYCLOPROPANECARBONITRILE, 97(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-BROMOPHENYL)CYCLOPROPANECARBONITRILE, 97(124276-67-1)
• EPA Substance Registry System: 1-(4-BROMOPHENYL)CYCLOPROPANECARBONITRILE, 97(124276-67-1)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl
• Hazardous Substances Data: 124276-67-1(Hazardous Substances Data)

Usage

General Description

1-(4-Bromophenyl)cyclopropanecarbonitrile, 97 refers to a specialized chemical compound denoted by the 97% purity level. It is characterized by a structure comprising a cyclopropane core along with a carbonitrile group and a 4-bromophenyl substitute. The inherent components of this compound, particularly the bromine atom and carbonitrile group, give it distinct chemical behavior. It is usually used in the exploration of varied synthesis techniques as well as in the broad realm of pharmaceuticals and pesticides. The compound is generally stored and handled under explicit safety measures due to its potential reactivity.

InChI:InChI=1/C11H9BrN2/c1-8-13-7-6-11(14-8)9-2-4-10(12)5-3-9/h2-7H,1H3

Upstream product

• 16532-79-9 4-Bromophenylacetonitrile 
• 107-04-0 1-Bromo-2-chloroethane 
• 96-49-1 [1,3]-dioxolan-2-one 
• 179251-27-5 1-bromo-4-(cyclopropylidenemethyl)benzene 
• 1122-91-4 4-bromo-benzaldehyde 
• 623-00-7 4-bromobenzenecarbonitrile 
• 56-37-1 N-benzyl-N,N,N-triethylammonium chloride 
• 106-93-4 ethylene dibromide 

Downstream Products

• 867330-28-7 1-{4-[7-(2,6-dimethyl-phenyl)-5-methyl-benzo[1,2,4]triazin-3-ylamino]-phenyl}-cyclopropanecarbonitrile 
• 26961-82-0 1-(4-Cyclohexyl-phenyl)-cyclopropanecarbonitrile 
• 1423694-19-2 C₂₈H₂₃N₂O₅^(1-)*Na⁽¹⁺⁾ 
• 1380587-34-7 1-{4'-[4-((R)-1-phenylethoxycarbonylamino)oxazol-5-yl]biphenyl-4-yl}cyclopropanecarboxylic acid 
• 1423694-17-0 C₂₉H₂₆N₂O₅ 
• 1423703-99-4 C₁₈H₁₇BrO₂ 
• 1423692-46-9 C₂₉H₂₆N₂O₄S 
• 1423703-97-2 C₂₁H₁₇NO₄S 
• 1423692-37-8 C₂₈H₂₂ClN₂O₄S^(1-)*Na⁽¹⁺⁾ 
• 1423685-52-2 C₂₈H₂₃ClN₂O₄S 
• 1423692-34-5 C₂₉H₂₅ClN₂O₄S 
• 1423703-95-0 C₂₁H₁₆ClNO₄S 
• 1423703-92-7 C₂₀H₁₄ClNO₄S 
• 1423703-90-5 C₂₂H₁₈ClNO₄S 

Relevant articles and documents

Photochemical Deracemization at sp3-Hybridized Carbon Centers via a Reversible Hydrogen Atom Transfer

A photochemical deracemization of 5-substituted 3-phenylimidazolidine-2,4-diones (hydantoins) is reported (27 examples, 69%-quant., 80–99% ee). The reaction is catalyzed by a chiral diarylketone which displays a two-point hydrogen bonding site. Mechanistic evidence (DFT calculations, radical clock experiments, H/D labeling) suggests the reaction to occur by selective hydrogen atom transfer (HAT). Upon hydrogen binding, one substrate enantiomer displays the hydrogen atom at the stereogenic center to the photoexcited catalyst allowing for a HAT from the substrate and eventually for its conversion into the product enantiomer. The product enantiomer is not processed by the catalyst and is thus enriched in the photostationary state.

Preparation method of arylcyclopropane compound

The present invention discloses a method for preparing an arylcyclopropane compound, 1.0eq phenylacetonitrile and 1.1eq 1-bromo-2-chloroethane as the starting material, N, N- dimethylacetamide as a solvent, solvent dosage of 10V, plus 2.5eq sodium hydride

Electrophilic Bromolactonization of Cyclopropyl Diesters Using Lewis Basic Chalcogenide Catalysts

An efficient and regioselective electrophilic bromolactonization of cyclopropylmethyl diesters using triphenylphosphine sulfide (Ph3PS) or diphenyl selenide (Ph2Se) as the Lewis basic chalcogenide catalyst has been developed. It was observed that Ph3PS favored the formation of anti-diastereomer and yielded the multi-functional γ-lactones. Interestingly, the diastereoselectivity was reversed when using Ph2Se as a catalyst where the syn-product instead of the anti-product was favored. (Figure presented.).