124278-65-5Relevant articles and documents
2-oxo-1-pyrrolidine carboxylic acid esters
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, (2008/06/13)
An improved process for the preparation of statine, the phenyl analog of statine, the cyclohexyl analog of statine and derivatives thereof is described, as well as other valuable intermediates used in the process.
STEREOSPECIFIC SYNTHESIS OF S,S-STATINE AND ITS CONGENERS
Klutchko, Sylvester,O'Brien, Patrick,Hodges, John C.
, p. 2573 - 2584 (2007/10/02)
Statine, (STA, 8) and its cyclohexyl analog (ACHPA, 9) are obtained by a stereospecific synthesis via tetramic acid chemistry.Amides of STA and ACHPA, useful for the synthesis of antihypertensive renin inhibitors, are prepared directly from the intermedia