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98105-45-4

98105-45-4

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  • L-threo-Pentonic acid,5-cyclohexyl-2,4,5-trideoxy-4-[[(1,1-dimethylethoxy)carbonyl]amino]-

    Cas No: 98105-45-4

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  • L-threo-Pentonic acid,5-cyclohexyl-2,4,5-trideoxy-4-[[(1,1-dimethylethoxy)carbonyl]amino]-

    Cas No: 98105-45-4

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98105-45-4 Usage

Chemical Properties

White powder

Uses

Boc-(3S,4S)-4-amino-3-hydroxy-5-cyclohexylpentanoic Acid, Boc-5-Cyclohexylstatine

Check Digit Verification of cas no

The CAS Registry Mumber 98105-45-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,1,0 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 98105-45:
(7*9)+(6*8)+(5*1)+(4*0)+(3*5)+(2*4)+(1*5)=144
144 % 10 = 4
So 98105-45-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H29NO5/c1-16(2,3)22-15(21)17-12(13(18)10-14(19)20)9-11-7-5-4-6-8-11/h11-13,18H,4-10H2,1-3H3,(H,17,21)(H,19,20)/t12-,13-/m0/s1

98105-45-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name BOC-ACHPA

1.2 Other means of identification

Product number -
Other names BOC-CYCLOHEXYLSTATINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:98105-45-4 SDS

98105-45-4Downstream Products

98105-45-4Relevant articles and documents

New potential renin inhibitors with dipeptide replacements in the molecule

Winiecka, Iwona,Dudkiewicz-Wilczynska, Jadwiga,Roman, Iza,Paruszewski, Ryszard

scheme or table, p. 367 - 374 (2011/08/04)

A series of eight non-peptidic potential renin inhibitors have been designed and synthesized. All of them contain dipeptide replacement: (3S,4S)-4-amino-5-cyclohexyl-3-hydroxypentanoic acid (ACHPA) in their molecules. Four among them comprise two additional analogs of dipeptide: (3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid (AHPPA) and (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid (statine, Sta). All of the synthesized compounds contain also hydrophobic portions to receive a moderate lipophilicity of the molecules. Inhibitory activity of the compounds was measured in vitro by HPLC determination of Leu-Val-Tyr-Ser released from the N-acetyltetradecapeptide substrate by renin in the presence of the inhibitor. Asp-α(OEt)-(S,S)-ACHPA-εAhx-Iaa (23) shows inhibitory activity (7%) at the concentration of 1.0 × 10-2 M. The other synthesized compounds show no inhibitory activity up to this concentration.

Renin inhibitors containing phenylalanyl-histidine replacements

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, (2008/06/13)

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Syntheses and biological activities of renin inhibitors containing statine analogues

Nishi,Saito,Nagahori,Kataoka,Morisawa,Yabe,Sakurai,Higashida,Shoji,Matsushita,Iijima,Ohizumi,Koike

, p. 103 - 109 (2007/10/02)

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