1242850-20-9

Upstream product

• 55661-08-0 4-methoxy-2,6-dimethylbenzenesulfonyl chloride 
• 1242850-18-5 (1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methanol 
• 1242850-17-4 ethyl 3,4-dihydropyrrolo[1,2-a]pyrazine-1-carboxylate 
• 1242850-16-3 ethyl 2-(2-(1H-pyrrol-1-yl)ethylamino)-2-oxoacetate 
• 29709-35-1 1-(2-aminoethyl)pyrrole 
• 73627-16-4 N-[2-(1H-pyrrol-1-yl)ethyl]acetamide 
• 1242850-19-6 (2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methanol 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 1242850-00-5 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)acetic acid 
• 1361581-73-8 2-[[2-[(4-methoxy-2,6-dimethyl-phenyl)sulfonyl]-1,2,3,4-tetrahydro-pyrrolo[1,2-a]pyrazin-1-yl]-methoxy]-N-methyl-N-[(1S,3R)-3-(4-methyl-piperazin-1-yl)-cyclohexyl]-acetamide 
• 1361581-76-1 2-[[2-[(4-methoxy-2,6-dimethyl-phenyl)sulfonyl]-1,2,3,4-tetrahydro-pyrrolo[1,2-a]pyrazin-1-yl]-methoxy]-N-methyl-N-[4-(4-methyl-piperazin-1-yl)-cyclohexyl]-acetamide 
• 1242847-50-2 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)-1-(2,8-diazaspiro[4.5]decan-8-yl)ethanone 
• 1242847-30-8 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)-1-(4-(1-methylpiperidin-4-yl)piperazin-1-yl)ethanone 
• 1242847-51-3 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)-1-((1R,3S,5S)-3-(pyridin-4-yloxy)-8-azabicyclo[3.2.1]octan-8-yl)ethanone 
• 1242847-32-0 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)-1-(2-(pyridin-4-yl)-2,8-diazaspiro[4.5]decan-8-yl)ethanone 
• 1242847-38-6 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)-1-(9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl)ethanone 
• 1242847-60-4 2-[[2-[(4-methoxy-2,6-dimethylphenyl)sulfonyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl]methoxy]-N-[1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl]acetamide 
• 1306758-55-3 C₂₉H₃₇F₃N₄O₆S 
• 1242847-52-4 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)-1-(4-(pyridin-3-yl)-4-(2-(pyrrolidin-1-yl)ethoxy)piperidin-1-yl)ethanone 

Relevant academic research and scientific papers

Substituted Tetrahydropyrrolopyrazine Compounds

Tetrahydropyrrolopyrazine compounds, methods for their preparation, pharmaceutical compositions containing such compounds, and a method of using such compounds for the treatment of pain and other conditions mediated at least partially by Bradykinin 1 rece

SUBSTITUTED TETRAHYDROPYRROLOPYRAZINE DERIVATIVES

The present invention relates to tetrahydropyrrolopyrazines, methods for the preparation thereof, medicaments containing these compounds and compounds for the use of treating, amongst other things, pain.

SULFONYLATED TETRAHYDROAZOLOPYRAZINES AND THEIR USE AS MEDICINAL PRODUCTS

The present invention relates to sulfonylated tetrahydroazolopyrazines, methods for the preparation thereof, medicinal products containing these compounds and the use of substituted indole compounds for the preparation of medicinal products (Formula I).