73627-16-4

Upstream product

• 696-59-3 cis,trans-2,5-dimethoxytetrahydrofuran 
• 64-19-7 acetic acid 
• 107-15-3 ethylenediamine 
• 1001-53-2 monoacetylaminoethylamine 

Downstream Products

• 29709-35-1 1-(2-aminoethyl)pyrrole 
• 64608-66-8 1-methyl-3,4-dihydropyrrolo[1,2-a]pyrazine 
• 73627-29-9 N-Ethyl-1-(2-aminoethyl)-pyrrole 
• 73627-24-4 1-Methyl-2-phenethyl-3,4-dihydro-pyrrolo[1,2-a]pyrazin-2-ium; bromide 
• 73627-18-6 1-Methyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 73627-19-7 1,2-Dimethyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 73627-30-2 2-Ethyl-1-phenyl-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 73627-23-3 1-Methyl-2-(2-phenylethyl)-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 73627-27-7 1-(3,4,5-Trimethoxyphenyl)-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 73627-32-4 2-Ethyl-1-(3,4,5-Trimethoxyphenyl)-1,2,3,4-tetrahydropyrrolo<1,2-a>pyrazine 
• 1242850-00-5 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)acetic acid 
• 1242850-19-6 (2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methanol 
• 1242850-20-9 ethyl 2-((2-(4-methoxy-2,6-dimethylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)acetate 
• 1242850-02-7 2-((2-(2-chloro-6-methylphenylsulfonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazin-1-yl)methoxy)acetic acid 

Relevant academic research and scientific papers

Preparation method of N- phenyl-2-aminopyrimidine compound and its application

The invention relates to a new N- phenyl-2-aminopyrimidine compound and a medicine composition containing the compound; the N- phenyl-2-aminopyrimidine compound is applied to treat related disease or symptoms of epidermal growth factor receptor (EGFR), such as treat or improve abnormal cell proliferative disease like cancer.

Substituted Tetrahydropyrrolopyrazine Compounds

Tetrahydropyrrolopyrazine compounds, methods for their preparation, pharmaceutical compositions containing such compounds, and a method of using such compounds for the treatment of pain and other conditions mediated at least partially by Bradykinin 1 rece

SUBSTITUTED TETRAHYDROPYRROLOPYRAZINE DERIVATIVES

The present invention relates to tetrahydropyrrolopyrazines, methods for the preparation thereof, medicaments containing these compounds and compounds for the use of treating, amongst other things, pain.

SULFONYLATED TETRAHYDROAZOLOPYRAZINES AND THEIR USE AS MEDICINAL PRODUCTS

The present invention relates to sulfonylated tetrahydroazolopyrazines, methods for the preparation thereof, medicinal products containing these compounds and the use of substituted indole compounds for the preparation of medicinal products (Formula I).

Design of chiral poly(pyrroles)

The synthesis of three 3-substituted and one N-substituted chiral pyrrole derivatives as well as their electropolymerization conditions are described. The new materials thus obtained possess recognition properties as enantioselective electrodes.

Tetracyclic pyrrole lactam derivatives

Disclosed are the compounds of formula I STR1 wherein R and R1 -R3 independently represent hydrogen or lower alkyl, and m represents the integer 2 or 3; their methods of preparation; pharmaceutical compositions thereof, and their use

Heterotertracyclic lactam derivatives, pharmaceutical compositions, and method of treating impaired memory and learning

Disclosed are the compounds of formula I: STR1 wherein R1 -R3 represent hydrogen or lower alkyl; m represents the integer 2 or 3; n represents the integer 1 or 2; Het represents a pyrrole or imidazole ring bonded at any two adjacent positions and optionally substituted by one or two or lower alkyl; and pharmaceutically acceptable salts of compounds of formula I wherein Het represents optionally substituted imidazole; their methods of preparation; pharmaceutical compositions thereof, and their use for treating cognitive disorders in mammals.

1,2,3,4-Tetrahydropyrrolo(1,2-A)pyrazines

1,2,3,4-tetrahydropyrrolo(1,2-a)pyrazine derivatives characterized by having a lower alkyl, cyclo(lower)alkyl, phenyl or substituted phenyl at position 1 of the nucleus and optionally further substituted at position 2 of the nucleus with a lower alkyl, cy