124469-06-3

Basic information

• Product Name: cis-2-phenyltetrahydropyran-6-carbonitrile
• CAS NO: 124469-06-3
• Molecular Weight: 187.241
• Mol File: 124469-06-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: cis-2-phenyltetrahydropyran-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: cis-2-phenyltetrahydropyran-6-carbonitrile(124469-06-3)
• EPA Substance Registry System: cis-2-phenyltetrahydropyran-6-carbonitrile(124469-06-3)

Safety Data

• Hazardous Substances Data: 124469-06-3(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 100-52-7 benzaldehyde 
• 129471-18-7 3-(1,3-dioxolan-2-yl)propyllithium 
• 4454-05-1 2-methoxy-3,4-dihydro-2H-pyran 
• 120749-57-7 cis-2-(benzenesulphonyl)tetrahydro-6-methoxy-2H-pyran 
• 120749-57-7 trans-2-(benzenesulphonyl)tetrahydro-6-methoxy-2H-pyran 
• 31357-97-8 trans-tetrahydro-2-methoxy-6-phenyl-2H-pyran 
• 124654-51-9 2-(benzenesulphonyl)tetrahydro-6-phenyl-2H-pyran 
• 124469-01-8 5-trimethylsiloxy-5-phenylpentanal 

Relevant articles and documents

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The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD.

Stereoselective Syntheses of α-Substituted Cyclic Ethers and syn-1,3-Diols

In the presence of a catalytic amount of triphenylmethylium hexachloroantimonate or a catalyst system of antimony pentachloride, chlorotrimethylsilane and tin(II)iodide, α-substituted cyclic ethers are stereoselectively prepared from lactones by successiv

SUBSTITUTION REACTIONS OF 2-BENZENESULPHONYL CYCLIC ETHERS WITH SILYL ENOL ETHERS PROMOTED BY ALUMINIUM TRICHLORIDE

Several cyclic ether 2-benzenesulphones were shown to react with silyl enol ethers in the presence of AlCl3 to give the corresponding alkylated products in good yield.Where substitution occured to give 2,6-disubstituted products there was a marked prefere