124526-56-3

Usage

Uses

Used in Organic Synthesis and Materials Science:
[1,1':3',1''-Terphenyl]-4,4''-diol is utilized as a key compound in organic synthesis and materials science due to its distinct terphenyl structure and the interesting properties it exhibits. Its versatility makes it a valuable component in the development of new materials and chemical processes.
Used in Liquid Crystal Production:
In the liquid crystal industry, [1,1':3',1''-Terphenyl]-4,4''-diol is used as a crucial component for the production of liquid crystals. Its unique molecular structure contributes to the desired characteristics of liquid crystal displays, making it an essential material in this application.
Used in Optoelectronic Devices:
[1,1':3',1''-Terphenyl]-4,4''-diol also shows potential for use in optoelectronic devices, where its properties can be harnessed to improve the performance and efficiency of these high-tech devices. Its application in this field is still under exploration, but the early findings are promising.
Used in Pharmaceutical and Biologically Active Molecules:
Furthermore, [1,1':3',1''-Terphenyl]-4,4''-diol has been studied for its potential application in the development of pharmaceuticals and biologically active molecules. Its unique structure and properties make it a candidate for creating new drugs and therapies, although more research is needed to fully understand its potential in this area.

Upstream product

• 1568-74-7 4,4’’-dimethoxy-1,1′:3′,1’’-terphenyl 
• 92-06-8 1,3-diphenylbenzene 
• 6051-22-5 1,3-bis-(4-methoxy-phenyl)-cyclohexane 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 108-36-1 1,3-dibromobenzene 
• 823-19-8 3-hydroxycyclohexanone 
• 100-66-3 methoxybenzene 
• 822-86-6 trans-1,2-dichlorocyclohexane 
• 5720-07-0 4-methoxyphenylboronic acid 

Relevant academic research and scientific papers

Synthesis of 3-arylmuconolactones using biphenyl metabolism in Aspergillus

Strains of the fungus Aspergillus form 3-arylmuconolactones as secondary products of the metabolism of biphenyl and substituted biphenyls. The 3-arylmuconolactones are not found to support growth and can accumulate to significant concentrations. The metabolic pathway leading from hydroxylated biphenyls to lactones appears to proceed through 3,4-catechol intermediates.

METHOD FOR PRODUCING 4,4''-DIHYDROXY-M-TERPHENYLS

To achieve the object of providing a new method of manufacturing 4,4 -dihydroxy-m-terphenyl, the present invention provides a method of manufacturing 4,4 -dihydroxy-m-terphenyl expressed by General Formula (4) below, characterized in that such method uses a 2-cyclohexene-1-one expressed by General Formula (1) below or 3-hydroxycyclohexane-1-one expressed by General Formula (2) below, and phenol expressed by General Formula (3) below as materials and implements Step (A), Step (B), and Step (C) below, in this order, or Step (D) and Step (C) below, in this order: (In the formulas, each R2 independently represents an alkyl group, alkoxy group, aromatic hydrocarbon group, or halogen atom, while m independently indicates 0 or an integer of 1 to 4, where R2 substitution does not occur in the third position when m is 1 or greater, and when m is 2 or greater, R2's may be identical or different, and R2 substitution does not occur in two positions of the same carbon atom. In addition, R2 and m in General Formula (1) may be identical to or different from R2 and m in General Formula (2), respectively.) (In the formula, each R1 independently represents an alkyl group, alkoxy group, aromatic hydrocarbon group, halogen atom, or hydroxyl group, while n indicates 0 or an integer of 1 to 4, where R1's may be identical or different when n is 2 or greater.) Step (A): Step to obtain a 1,1,3-trisphenol by causing the 2-cyclohexene-1-one or 3-hydroxycyclohexane-1-one and phenol to react with each other in the presence of a catalyst. Step (B): Step to obtain a bis(4-hydroxyphenyl)cyclohexene by causing the 1,1,3-trisphenol to undergo breakdown reaction. Step (C): Step to obtain a 4,4 -dihydroxy-m-terphenyl by dehydrogenating the bis(4-hydroxyphenyl)cyclohexene. Step (D): Step to obtain a bis(4-hydroxyphenyl)cyclohexene by causing the 2-cyclohexene-1-one or 3-hydroxycyclohexane-1-one and phenol to react with each other in the presence of a catalyst. (In the formula, each R1 and n is independently the same as the corresponding items in General Formula (3), respectively, while R2 and m are the same as the corresponding items in General Formula (1) or General Formula (2), respectively.)

NOVEL DICYANATE ESTER COMPOUND

PROBLEM TO BE SOLVED: To provide novel dicyanate ester compounds which are excellent in heat resistance, humidity resistance and flame resistance, compared with known dicyanate ester compounds, have a low melting point and excellent solubility, compared with the p-terphenyl skeleton and exert excellent heat resistance, humidity resistance and substrate adhesion when used as a raw material for a curable resin. SOLUTION: Dicyanate ester compounds are of formula (1) and has a m-terphenyl skeleton. In formula (1), R1, R2 and R3 are independently an alkyl group, an alkoxy group, a phenyl group or a halogen atom; l, m and n are independently 0 or an integer of 1-4; for l equal to or greater than 2, R1's may be identical or different; for m equal to or greater than 2, R2's may be identical or different; and for n equal to or greater than 2, R3's may be identical or different. COPYRIGHT: (C)2015,JPO&INPIT

Novel estrogen receptor (ER) modulators containing various hydrophobic bent-core structures

We previously discovered m-carborane-containing estrogen receptor (ER) modulator 4, which exhibits weak ER-agonistic and antagonistic activities in transactivation assays. With the aim of developing novel ER partial agonists, we designed and synthesized v

Polymerizable compound and liquid crystal composition including it

Provided is a polymerizable compound with large solubility in a liquid crystal composition and high reactivity irradiated by ultraviolet in the longer wavelength range. Provided is a liquid crystal composition that satisfies at least one of characteristics such as high maximum temperature of a nematic phase, low minimum temperature of a nematic phase, small viscosity, suitable optical anisotropy, large negative dielectric anisotropy, large specific resistance, high stability to ultraviolet light and high stability to heat, or that is suitably balanced between at least two of the characteristics. Provided is the polymerizable compound wherein at least one of a 1,3-phenylene structure and a 2,7-fluorenediyl structure is introduced to the polymerizable compound to give stable displays by forming a polymer with a high degree of polymerization in a PSA device production process using longer wavelengths, the liquid crystal composition includes the compound, and the liquid crystal display device contains the composition.

17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITORS FOR THE TREATMENT OF HORMONE-RELATED DISEASES

The invention relates to 17beta-hydroxysteroid dehydrogenase type 1 (17betaHSD1) inhibitors, the preparation thereof and the use thereof for the treatment and prophylaxis of hormone-related, especially estrogen-related or androgen-related, diseases.

Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1)

17β-Estradiol (E2), the most potent female sex hormone, stimulates the growth of mammary tumors and endometriosis via activation of the estrogen receptor α (ERα). 17β-Hydroxysteroid dehydrogenase type 1 (17β-HSD1), which is responsible for the catalytic r

Thermosensitive recording material and color developer compound therefor

A thermosensitive recording material has a support and a thermosensitive coloring layer formed thereon containing a leuco dye and a color developer capable of inducing color formation in the leuco dye upon application of heat thereto, with the color developer including at least one compound (A) having in a molecule thereof at least two aromatic ring moieties with specific structures, selected from the group consisting of an aromatic ring moiety having at least one carboxyl group and electron-attracting functional group, an aromatic ring moiety having at least one carboxyl group and electron-donating functional group, and an aromatic ring moiety having at least one carboxyl group, free of the electron-attracting and electron-donating functional groups. An aromatic carboxylic acid compound serving as the above-mentioned compound (A) and the producing method thereof are also disclosed.

Molecular design of nonchiral bent-core liquid crystals with antiferroelectric properties

Novel bent-core (banana-shaped) liquid crystals without Schiff-base units have been synthesized and investigated by polarized light optical microscopy, differential scanning calorimetry, X-ray scattering, and electrooptical investigations. These molecules are 4-(4- alkylbenzoyloxy)benzoates and 4-(4-alkoxybenzoyloxy)benzoates of resorcinol, 3,4'-dihydroxybiphenyl, and 4,4'-dihydroxy- 1,1':3', 1'-terphenyl. Three different mesophases were found depending on the molecular structure and the length of the terminal alkyl chains: a rectangular columnar phase, a highly ordered low-temperature mesophase, and an antiferroelectric switchable fluid smectic mesophase designated as SmCP(A). The influence of the molecular structure on the occurrence of the SmCP(A) phase was investigated. The spontaneous polarization of these molecules is quite high (P(s) = 500700 nC cm-2) and specially those molecules with long alkyl chains and short bent- core structures have low melting points and broad regions of this switchable mesophase. Furthermore, first examples of antiferroelectric switchable bent- core molecules with semifluorinated terminal chains will be described.

Designing banana-shaped liquid crystals without Schiff's base units: m- Terphenyls, 2,6-diphenylpyridines and V-shaped tolane derivatives

This paper reports attempts to obtain (anti)ferroelectric switchable achiral banana-shaped molecules without Schiff's base units. For this purpose we have synthesized novel V-shaped molecules consisting of rigid angular central units [1,3-disubstituted be