1246030-06-7

Usage

Uses

Used in Pharmaceutical Industry:
Tert-butyl 2-carbaMoylpiperazine-1-carboxylate is used as a precursor in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows for the creation of molecules with specific biological activities, making it a valuable component in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical field, tert-butyl 2-carbaMoylpiperazine-1-carboxylate is utilized as a starting material for the synthesis of pesticides. Its chemical properties enable the production of effective compounds designed to protect crops and control pests, thereby enhancing agricultural productivity.
Used in Organic Chemistry Research:
Tert-butyl 2-carbaMoylpiperazine-1-carboxylate serves as a key intermediate in organic chemistry research, facilitating the exploration of novel chemical reactions and the synthesis of complex organic molecules. Its versatility as a building block makes it instrumental in advancing the field of organic synthesis.

Upstream product

• 252990-05-9 1-(tert-butyl) 2-methyl (R)-piperazine-1,2-dicarboxylate 
• 796096-64-5 (S)-piperazine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 67-56-1 methanol 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 129799-15-1 piperazine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 

Downstream Products

• 927883-45-2 2-carbamoylpiperazine-1,4-dicarboxylic acid di-tert-butyl ester 

Relevant academic research and scientific papers

METALLO-BETA-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to metallo-β-lactamase inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-β-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more β-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.

Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines

The present invention discloses aromatic heterocyclic derivatives and applications of the aromatic heterocyclic derivatives in medicines, and specifically provides a class of aromatic heterocyclic compounds or stereoisomers, geometric isomers, tautomers, racemic bodies, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the compounds. The present invention further discloses uses of the compounds or pharmaceutical compositions in drug preparation, wherein the drug is used for treatment of respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).

HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

Disclosed are heteroaryl derivatives, pharmaceutical composition and uses in the manufacture of a medicine for treating respiratory diseases, especially for chronic obstructive pulmonary disease (COPD).