124604-06-4Relevant academic research and scientific papers
Magnesium Monoperphthalate (MMPP): a Convenient Oxidant for the Direct Rubottom Oxidation of Malonates, β-Keto Esters, and Amides
Meninno, Sara,Villano, Rosaria,Lattanzi, Alessandra
, p. 1758 - 1762 (2021)
A mild and convenient protocol for the α-hydroxylation of α-substituted malonates, β-ketoesters, and β-ketoamides is disclosed. Cheap and stable magnesium monoperphthalate (MMPP) was effective for a first direct α-hydroxylation protocol of the Rubottom oxidation, providing tartronic esters, cyclic α-hydroxy β-ketoesters and amides in good to high yields, when working at room temperature and in ethanol as the solvent. The protocol has been successfully scaled up to gram quantity.
α-Hydroxylation of 1,3-dicarbonyl compounds catalyzed by polymer-incarcerated gold nanoclusters with molecular oxygen
Miyamura, Hiroyuki,Kobayashi, Shu
supporting information, p. 976 - 978 (2012/10/30)
α-Hydroxylation of 1,3-dicarbonyl compounds was successfully catalyzed by carbon-stabilized polymer-incarcerated gold nanoclusters (PI/CB-Au). The reaction proceeded under mild conditions using molecular oxygen as oxidant with wide substrate scopes and the catalyst could be recovered and reused by a simple operation. The control experiments and the reaction monitoring revealed that α-peroxide compounds were reaction intermediates, and PI/CB-Au also catalyzed isomerization.
Direct conversion of α,β-unsaturated nitriles into cyanohydrins using Mn(dpm)3 catalyst, dioxygen and phenylsilane
Magnus, Philip,Scott, David A.,Fielding, Mark R.
, p. 4127 - 4129 (2007/10/03)
Treatment of α,β-unsaturated nitriles with Mn(dpm)3 (3 mol%), PhSiH3 in isopropyl alcohol in the presence of oxygen resulted in reduction and α- and β-hydroxylation.
Electrochemical Hydroxylation, Methoxylation, and Hydroxymethylation of Active Methine Compounds
Kawabata, Jin-ichi,Nozawa, Koohei,Kawai, Ken-ichi,Nakajima, Shoichi
, p. 181 - 183 (2007/10/02)
Hydroxylation, methoxylation, or hydroxymethylation at the active methine group of phenylmalonate, benzylmalonate and diphenylacetate were achieved by anodic oxidation.
