124604-06-4

Basic information

• Product Name: dimethyl 2-hydroxy-2-benzylmalonate
• Synonyms: dimethyl 2-hydroxy-2-benzylmalonate
• CAS NO: 124604-06-4
• Molecular Weight: 238.24
• Mol File: 124604-06-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: dimethyl 2-hydroxy-2-benzylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-hydroxy-2-benzylmalonate(124604-06-4)
• EPA Substance Registry System: dimethyl 2-hydroxy-2-benzylmalonate(124604-06-4)

Safety Data

• Hazardous Substances Data: 124604-06-4(Hazardous Substances Data)

Upstream product

• 6626-84-2 dimethyl 2-benzylidenepropanedioate 
• 49769-78-0 2-benzyl-malonic acid dimethyl ester 
• 100-39-0 benzyl bromide 
• 108-59-8 malonic acid dimethyl ester 
• 124-41-4 sodium methylate 
• 607-81-8 diethyl 2-benzylmalonate 

Downstream Products

• 124604-07-5 dimethyl O-methylbenzyltartronate 

Relevant articles and documents

Magnesium Monoperphthalate (MMPP): a Convenient Oxidant for the Direct Rubottom Oxidation of Malonates, β-Keto Esters, and Amides

A mild and convenient protocol for the α-hydroxylation of α-substituted malonates, β-ketoesters, and β-ketoamides is disclosed. Cheap and stable magnesium monoperphthalate (MMPP) was effective for a first direct α-hydroxylation protocol of the Rubottom oxidation, providing tartronic esters, cyclic α-hydroxy β-ketoesters and amides in good to high yields, when working at room temperature and in ethanol as the solvent. The protocol has been successfully scaled up to gram quantity.

Direct conversion of α,β-unsaturated nitriles into cyanohydrins using Mn(dpm)3 catalyst, dioxygen and phenylsilane

Treatment of α,β-unsaturated nitriles with Mn(dpm)3 (3 mol%), PhSiH3 in isopropyl alcohol in the presence of oxygen resulted in reduction and α- and β-hydroxylation.