124750-59-0Relevant academic research and scientific papers
PROCESS FOR (5-METHYL-2-OXO-1,3-DIOXOLEN-4-YL)METHYL4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-1-[4-[2-TETRAZOL-5-YL)PHENYL]PHENYL]METHYLIMIDAZOLE-5-CARBOXYLATE
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Page/Page column 18, (2011/04/13)
The present invention relates to an improved process for the preparation of (5-methyl-2-oxo- 1,3-dioxolen-4-yl)methyl4-(1-hydroxy- 1-methylethyl)-2-propyl-1-[4-[2-(tetrazol-5-yl)phenyl]phenyl]methyl imidazole-5-carboxylate.
Efficient synthesis of olmesartan medoxomil, an antihypertensive drug
Babu, Karrothu Srihari,Reddy, Mallepalli Srinivasa,Tagore, Amirisetty Ravindranath,Reddy, Gade Srinivas,Sebastian, Sony,Varma, Mudunuru Satish,Venkateswarlu, Gandu,Bhattacharya, Apurba,Reddy, Padi Pratap,Anand, Ramasamy Vijaya
experimental part, p. 291 - 298 (2009/05/07)
This document describes a simple and robust process for the synthesis of olmesartan medoxomil. This tailored process allows us to synthesize olmesartan medoxomil on a large scale with 50% overall yield. Also, our process has excellent control of the impurity profile in all the stages. Copyright Taylor & Francis Group, LLC.
PROCESS FOR PREPARING OLMESARTAN MEDOXOMIL
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Page/Page column 19-20, (2008/06/13)
A process for preparing olmesartan medoxomil.
Fused aryl substituted imidazole angiotensin II receptor inhibitors
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, (2008/06/13)
Substituted imidazoles such as STR1 which are useful as angiotensin II receptor inhibitors. These compounds have activity in treating hypertension and congestive heart failure.
ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES
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, (2008/06/13)
Substituted imidazoles such as STR1 are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.
Treatment of congestive heart failure with angiotensin 11 receptor blocking imidazoles
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, (2008/06/13)
Substituted imidazoles such as STR1 are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.
