124750-59-0

Basic information

• Product Name: 2-Propyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester
• Synonyms: 2-propyl-1h-imidazole-4,5-dicarboxylic acid dimethyl ester;1H-imidazole-4,5-dicarboxylic acid,2-propyl-,dimethyl ester;2-Propyl-4,5-Dimethoxycarboxyl Imidazole;2-Propyl-Imidazole-4,5-Dicarboxylic Acid Dimethyl Ester;Dimethyl-2-propylimidazole-4,5-dicarboxylate;2-PROPYL-4,5-IMIDAZOLEDICARBOXYLIC ACID DIMETHYL ESTER 98.0%;1H-IMidazole-4,5-dicarboxylicacid, 2-propyl-, 4,5-diMethyl ester;DiMethyl 2-propyl-1H-iMidazole-4,5-dicarboxylate
• CAS NO: 124750-59-0
• Molecular Formula: C₁₀H₁₄N₂O₄
• Molecular Weight: 226.23
• EINECS: 1806241-263-5
• Product Categories: Organic acids
• Mol File: 124750-59-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 152-155 °C
• Boiling Point: 377.8 °C at 760 mmHg
• Flash Point: 182.3 °C
• Appearance: /
• Density: 1.215 g/cm³
• Vapor Pressure: 6.58E-06mmHg at 25°C
• Refractive Index: 1.519
• Storage Temp.: 2-8°C
• PKA: 8.96±0.10(Predicted)
• CAS DataBase Reference: 2-Propyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester(124750-59-0)
• EPA Substance Registry System: 2-Propyl-1H-imidazole-4,5-dicarboxylic acid dimethyl ester(124750-59-0)

Safety Data

• Hazardous Substances Data: 124750-59-0(Hazardous Substances Data)

Usage

Chemical Properties

White or off-white crystalline powder

InChI:InChI=1/C10H14N2O4/c1-4-5-6-11-7(9(13)15-2)8(12-6)10(14)16-3/h4-5H2,1-3H3,(H,11,12)

Upstream product

• 67-56-1 methanol 
• 58954-23-7 2-propyl-1H-imidazole-4,5-dicarboxylic acid 

Downstream Products

• 1020157-01-0 (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl4-(1-hydroxy-1-methylethyl)-2-propyl-1-[2′-(2-triphenylmethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl-1H-imidazole-5-carboxylate 
• 144689-63-4 olmesartan 
• 150691-01-3 4,5-Bis(methoxycarbonyl)-1-(4-bromophenyl)methyl-2-propylimidazole 
• 124750-61-4 2-propyl-1-[2'-(1-triphenylmethyl-1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-imidazole-4,5-dicarboxylic acid dimethyl ester 

Relevant articles and documents

PROCESS FOR (5-METHYL-2-OXO-1,3-DIOXOLEN-4-YL)METHYL4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-1-[4-[2-TETRAZOL-5-YL)PHENYL]PHENYL]METHYLIMIDAZOLE-5-CARBOXYLATE

The present invention relates to an improved process for the preparation of (5-methyl-2-oxo- 1,3-dioxolen-4-yl)methyl4-(1-hydroxy- 1-methylethyl)-2-propyl-1-[4-[2-(tetrazol-5-yl)phenyl]phenyl]methyl imidazole-5-carboxylate.

PROCESS FOR PREPARING OLMESARTAN MEDOXOMIL

A process for preparing olmesartan medoxomil.

ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES

Substituted imidazoles such as STR1 are useful as angiotensin II blockers. These compounds have activity in treating hypertension and congestive heart failure.