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144689-63-4

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Factory olmesartan medoxomil in stock CAS 144689-63-4
Cas No: 144689-63-4
No Data 1 Kilogram 10 Metric Ton/Month Shaanxi wuzhiyuan biotech co.,LTD Contact Supplier
Olmesartan Medoxomil
Cas No: 144689-63-4
No Data 1 Gram 5 Metric Ton/Day Shanghai SE Pharm Co., Ltd Contact Supplier
Olmesartan medoxomil Manufacturer/High quality/Best price/In stock
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USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
High quality Olmesartan Medoxomil
Cas No: 144689-63-4
USD $ 1.0-1.0 / Kilogram 10 Kilogram 50 Metric Ton/Day Hubei Jusheng Technology Co., Ltd., Contact Supplier
CAS:144689-63-4 Olmesartan medoxomil
Cas No: 144689-63-4
No Data 1 Kilogram 100 Kilogram/Week Kono Chem Co.,Ltd Contact Supplier
99% Pharmaceutical Antihypertensive Raw Powder Olmesartan
Cas No: 144689-63-4
USD $ 0.9-1.0 / Gram 10 Gram 1000 Kilogram/Month Hubei Yuancheng Saichuang Technology Co., Ltd Contact Supplier
Olmesartan Medoxomil 144689-63-4
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USD $ 10.0-10.0 / Kilogram 1 Kilogram 800 Metric Ton/Month Crovell Biotech (Hebei) Co., Ltd. Contact Supplier
Olmesartan medoxomil
Cas No: 144689-63-4
USD $ 200.0-300.0 / Kilogram 1 Kilogram 10000 Kilogram/Month Chengdu Yanxi Import & Export Trading CO.,LTD Contact Supplier
Factory supply OlmesartanMedoxomiI
Cas No: 144689-63-4
USD $ 1.0-2.0 / Metric Ton 1 Metric Ton 500 Metric Ton/Week Hebei yanxi chemical co.,LTD. Contact Supplier
CS-866 (Olmesartan medoxomil)
Cas No: 144689-63-4
No Data 1 Kilogram 1 Metric Ton/Month Henan Tianfu Chemical Co., Ltd. Contact Supplier

144689-63-4 Usage

Uses

Olmesartan medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion.
Olmesartan medoxomil is a pro-drug that is de-esterified to the active metabolite, olmesartan. Olmesartan has a dual method of elimination, with about 60% eliminated by the liver and the remainder by the kidney. In situations of impaired renal or hepatic function, the alternative excretion pathway can compensate for the compromised one. Olmesartan is not metabolized by the cytochrome P450 enzyme system and therefore has a low potential for metabolic drug interactions, a feature that may be of importance when treating patients on multiple drug regimens, such as the elderly. Olmesartan is well tolerated and has an excellent safety profile that is comparable to that of placebo. In addition, olmesartan provides 24-h blood pressure control with a once-daily dosing. In head-to-head studies, olmesartan delivered superior blood pressure reduction when compared with other angiotensin-II receptor antagonists at their recommended doses.

Uses

An angiotensin II receptor antagonist. Used as an anti-hypertensive

Chemical Properties

White to off-white crystalline powder

144689-63-4 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (SML1391)  Olmesartan medoxomil  ≥98% (HPLC) 144689-63-4 SML1391-250MG 3,970.98CNY Detail
Sigma (SML1391)  Olmesartan medoxomil  ≥98% (HPLC) 144689-63-4 SML1391-50MG 983.97CNY Detail
USP (1478367)  Olmesartan medoxomil  United States Pharmacopeia (USP) Reference Standard 144689-63-4 1478367-100MG 9,810.45CNY Detail
Sigma-Aldrich (Y0001424)  Olmesartan medoxomil for system suitability  European Pharmacopoeia (EP) Reference Standard 144689-63-4 Y0001424 1,880.19CNY Detail
Sigma-Aldrich (Y0001405)  Olmesartan medoxomil  European Pharmacopoeia (EP) Reference Standard 144689-63-4 Y0001405 1,880.19CNY Detail

144689-63-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Olmesartan medoxomil

1.2 Other means of identification

Product number -
Other names Olmesartan Medoxomil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144689-63-4 SDS

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