124887-14-5

Upstream product

• 105365-06-8 methyl 3,5-dihydoxy-2,4-dimethylpentanoate 
• 89329-05-5 1-methyl hydrogen (3S,2R,4S)-3-hydroxy-2,4-dimethylglutarate 
• 105365-07-9 methyl (2R,3S,4R)-3,5-(isopropylidenedioxy)-2,4-dimethylpentanoate 
• 81470-77-1 (2S,3R,4R)-1-(benzyloxy)-3,5-(isopropylidenedioxy)-2,4-dimethylpentane 
• 132950-30-2 (2S,4R)-1-(benzyloxy)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentan-3-one 
• 102849-23-0 (+)-(2R,3S,4S)-1,3,5-trihydroxy-2,4-dimethylpentane 3,5-acetonide 
• 132950-29-9 (2S,3R,4R)-1-(benzyloxy)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentan-3-ol 
• 132950-29-9 (2S,3S,4R)-1-(benzyloxy)-5-<(tert-butyl)diphenylsilyloxy>-2,4-dimethylpentan-3-ol 
• 124887-13-4 (2S,3R,4R)-5-(tert-butyldiphenylsiloxy)-2,4-dimethylpentane-1,3-diol 
• 77-76-9 2,2-dimethoxy-propane 
• 89395-27-7 (3R,4S,5R)-4-hydroxy-3,5-dimethyl-tetrahydro-(2H)-pyran-2-one 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 124887-12-3 methyl (2R,3S,4R)-5-(tert-butyldiphenylsiloxy)-3-hydroxy-2,4-dimethylpentanoate 
• 209250-90-8 (2R,3R,4R)-5-(tert-Butyl-diphenyl-silanyloxy)-3-hydroxy-2,4-dimethyl-pentanal 

Downstream Products

• 132950-32-4 2,6-dimethylphenyl (2R,3R,4S,5S,6S)-3,5,7-trihydroxy-2,4,6-trimethylheptanoate 
• 132950-31-3 2,6-dimethylphenyl (2R,3R,4R,5S,6S)-3-hydroxy-5,7-(isopropylidenedioxy)-2,4,6-trimethylheptanoate 
• 132950-35-7 2,6-dimethylphenyl (2R,3R,4S,5S,6S)-7-hydroxy-3,5-(isopropylidenedioxy)-2,4,6-trimethylheptanoate 
• 132950-36-8 2,6-dimethylphenyl (2R,3R,4S,5S,6S)-3,5-(isopropylidenedioxy)-2,4,6-trimethyl-7-oxoheptanoate 
• 132950-37-9 bis(2,6-dimethylphenyl) (2S,3S,4R,5R,6S,7R,8R)-3,5,7-trihydroxy-2,4,6,8-tetramethyl-nonane-1,9-dioate 
• 132950-33-5 2,6-dimethylphenyl (2R,3R,4S,5S,6S)-7-<(tert-butyl)diphenylsilyloxy>-3,5-dihydroxy-2,4,6-trimethylheptanoate 
• 105365-13-7 bis(2,6-dimethylphenyl) (2S,3S,4S,5S,6S,7R,8R)-5,7-(isopropylidenedioxy)-2,4,6,8-tetramethyl-nonane-1,9-dioate 
• 132950-34-6 2,6-dimethylphenyl (2R,3R,4S,5S,6S)-7-<(tert-butyl)diphenylsilyloxy>-3,5-(isopropylidenedioxy)-2,4,6-trimethylheptanoate 
• 135681-55-9 2',6'-dimethylphenyl (2R,3R,4R,5R,6S)-3-hydroxy-5,7-isopropylidenedioxy-2,4,6-trimethylheptanonate 

Relevant academic research and scientific papers

Enantioselective synthesis of anti - And syn -homopropargyl alcohols via chiral Br?nsted acid catalyzed asymmetric allenylboration reactions

Chiral Br?nsted acid catalyzed asymmetric allenylboration reactions are described. Under optimized conditions, anti-homopropargyl alcohols 2 are obtained in high yields with excellent diastereo- and enantioselectivities from stereochemically matched aldeh

Stereoselective synthesis of a building block corresponding to the C(1)-to-C(7) moiety of 14-membered macrolide antibiotics

The synthesis of 2',6'-dimethylphenyl (2R,3R,4R,5R,6S)-3-hydroxy-5,7-isopropylidenedioxy-2,4,6-trimethylhepta noate (13) a synthon for the C(1)-to-C(7) segment of a number of 14-membered macrolide antibiotics is described, starting from the meso-diester 3

SYNTHESIS OF A VERSATILE CHIRAL SYNTHON CORRESPONDING TO THE C(1) to C(7) SEGMENT OF 14-MEMBERED MACROLIDE ANTIBIOTICS

The synthesis of the C(1) to C(7) segment of a number of 14-membered macrolide antibiotics is described, starting from dimethyl 3-hydroxy-2,4-dimethylglutarate.