125032-07-7

Upstream product

• 125032-05-5 (1R^*,2S^*,4R^*)-4-(benzyloxy)-2-bromo-1-(3,4-dimethoxyphenyl)cyclohexan-1-ol 
• 129920-37-2 (1R^*,2S^*,4R^*)-4-(benzyloxy)-1,2-epoxy-1-(3,4-dimethoxyphenyl)cyclohexane 
• 2859-78-1 4-Bromoveratrole 
• 2987-06-6 4-(benzyloxy)cyclohexanone 
• 82732-16-9 4-(benzyloxy)-1-(3,4-dimethoxyphenyl)cyclohex-1-ene 
• 79-36-7 dichloroacethyl chloride 
• 125032-06-6 (1R^*,2S^*,4R^*)-4-(benzyloxy)-1-(3,4-dimethoxyphenyl)-2-(methylamino)cyclohexan-1-ol 

Downstream Products

• 21104-32-5 (3aR,7aR)-3a-(3,4-Dimethoxy-phenyl)-6-hydroxy-1-methyl-octahydro-indol-2-one 
• 82769-20-8 (+/-)-6-epimesembranol 
• 6023-73-0 mesembrine 
• 82769-19-5 (+/-)-mesembranol 
• 125032-10-2 (1S^*,5R^*)-N-<5-(benzyloxy)-2-(3,4-dimethoxyphenyl)cyclohex-2-en-1-yl>-N-methylacetamide 
• 82732-18-1 (3aR^*,6R^*,7aS^*)-6-(benzyloxy)octahydro-3a-(3,4-dimethoxyphenyl)-1-methylindol-2-one 
• 82732-19-2 (3aR^*,6R^*,7aS^*)-6-(benzyloxy)octahydro-3a-(3,4-dimethoxyphenyl)-1-methylindole 
• 125032-09-9 N-<5-(benzyloxy)-2-(3,4-dimethoxyphenyl)cyclohex-1-en-1-yl>-α,α-dichloro-N-methylacetamide 
• 125032-08-8 (1S^*,5R^*)-N-<5-(benzyloxy)-2-(3,4-dimethoxyphenyl)cyclohex-2-en-1-yl>-α,α-dichloro-N-methylacetamide 

Relevant academic research and scientific papers

Radical Cyclization of N-(Cyclohex-2-enyl)-α,α-dichloroacetamides. Stereoselective Syntheses of (+/-)-Mesembranol and (+/-)-Elwesine

Stereoselective syntheses of the Sceletium alkaloid (+/-)-mesembranol (2) and the Amaryllidaceae alkaloid (+/-)-elwesine (3) have been achieved.A key step in the syntheses involves the Bu3SnH-mediated radical cyclization of the dichloroacetamides 34 and 4

Synthesis of (+/-)-Mesembranol by Radical Cyclisation of α,α-Dichloroacetamides

(+/-)-Mesembranol was synthesised in a highly stereoselective manner using Bu3SnH mediated radical cyclisation of α,α-dichloroacetamide as the key step.