125552-56-9

Usage

Derivative of pyrrolidinecarboxylic acid

1-Pyrrolidinecarboxylic acid, 3-azido-, 1,1-dimethylethyl ester, (3S)is a chemical compound that is a derivative of pyrrolidinecarboxylic acid, which is a naturally occurring amino acid in the human body.

Ester formation

The compound is an ester, meaning it is formed from the condensation of an acid and an alcohol.

(3S)-stereoisomer

The 3S designation indicates that it is the (3S)-stereoisomer of the molecule.

Azide group

The 3-azido modification indicates the presence of an azide group, which is a functional group containing three nitrogen atoms.

Used in chemical and pharmaceutical research

1-Pyrrolidinecarboxylic acid, 3-azido-, 1,1-dimethylethyl ester, (3S)is commonly used in chemical and pharmaceutical research.

Potential applications in drug development and organic synthesis

The compound has potential applications in drug development and organic synthesis due to its unique structure and properties.

Potentially hazardous and explosive

It is important to handle 1-Pyrrolidinecarboxylic acid, 3-azido-, 1,1-dimethylethyl ester, (3S)- with care, as azides can be potentially hazardous and explosive.

Upstream product

• 127423-61-4 tert-butyl (3R)-3-methylsulfonyloxypyrrolidine-1-carboxylate 
• 101469-92-5 (S)-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 139986-03-1 1,1-dimethylethyl-3(R)-{[(4-methylphenyl)sulphonyl]oxy}-1-pyrrolidinecarboxylate 
• 109431-87-0 (R)-tert-butyl 3-hydroxypyrrolidine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 132945-75-6 (S)-tert-butyl 3-(methylsulfonyloxy)pyrrolidine-1-carboxylate 

Downstream Products

• 193269-79-3 tert-butyl (3S)-3-(2-aminoacetylamino)-1-pyrrolidinecarboxylate 
• 114636-37-2 tert-butyl (3S)-3-acetamidopyrrolidine-1-carboxylate 
• 1352660-47-9 C₂₆H₃₀N₆O₁₀ 
• 1352660-62-8 C₁₆H₂₂N₂O₄ 
• 1352660-22-0 C₁₇H₂₃N₃O₆ 
• 147081-44-5 (3S)-3-amino-1-(tert-butoxycarbonyl)-pyrrolidine 

Relevant academic research and scientific papers

Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines

The present invention discloses aromatic heterocyclic derivatives and applications of the aromatic heterocyclic derivatives in medicines, and specifically provides a class of aromatic heterocyclic compounds or stereoisomers, geometric isomers, tautomers, racemic bodies, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the compounds. The present invention further discloses uses of the compounds or pharmaceutical compositions in drug preparation, wherein the drug is used for treatment of respiratory diseases, particularly chronic obstructive pulmonary disease (COPD).

HETEROAROMATIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF

Disclosed are heteroaryl derivatives, pharmaceutical composition and uses in the manufacture of a medicine for treating respiratory diseases, especially for chronic obstructive pulmonary disease (COPD).

CARBAPENEM ANTIBACTERIALS WITH GRAM-NEGATIVE ACTIVITY

The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

Anti-infective compounds

The present invention relates to small molecule compounds and their use in the treatment of bacterial infections, in particular Tuberculosis.

METHOD AND COMPOSITIONS FOR TREATING HIV INFECTIONS

Described herein are compounds and compositions that are useful in the treatment of HIV, AIDS, and AIDS-related diseases. In addition, compounds are described herein that are capable of inhibiting the dimerization of HIV proteases.

3-AMINOPYRROLIDINES AS INHIBITORS OF MONOAMINE UPTAKE

The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, which are useful for the inhibition of the uptake of one or more physiologically active monoamines (serotonin, norepinephrine, and dopamine).

TREATMENT OF LEARNING DISABILITIES AND MOTOR SKILLS DISORDER WITH NOREPINEPHRINE REUPTAKE INHIBITORS

Provided are methods and medicaments for treating a learning disability or a Motor Skills Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.

TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS

Provided are methods and medicaments for treating a Pervasive Developmental Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.

TREATMENT OF HOT FLASHES, IMPULSE CONTROL DISORDERS AND PERSONALITY CHANGE DUE TO A GENERAL MEDICAL CONDITION

Selective norepinephrine reuptake inhibitors are useful for the prevention or treatment of hot flashes, vasomotor symptoms, impulse control disorders or personality change due to a general medical condition.