1255666-86-4 Usage
Uses
Used in Pharmaceutical Industry:
5,5-Difluoro-1,3-piperidinedicarboxylic acid tert-butyl ester is used as a key intermediate for the synthesis of various pharmaceuticals and drug candidates due to its unique structure containing fluorine atoms and a piperidine ring, which are beneficial for the development of new medications with improved properties.
Used in Organic Synthesis:
5,5-Difluoro-1,3-piperidinedicarboxylic acid tert-butyl ester is used as a versatile building block in organic synthesis for the production of fluorinated organic compounds. The presence of fluorine atoms in its structure enhances the reactivity and stability of the resulting compounds, making it a valuable precursor in the synthesis of various organic molecules.
Used in Drug Development:
5,5-Difluoro-1,3-piperidinedicarboxylic acid tert-butyl ester is used as a starting material in drug development for the creation of new drug candidates with potential therapeutic applications. Its unique structure allows for the design of novel compounds with improved pharmacological properties, such as increased potency, selectivity, and bioavailability.
Used in Medicinal Chemistry Research:
5,5-Difluoro-1,3-piperidinedicarboxylic acid tert-butyl ester is used as a research tool in medicinal chemistry to explore the structure-activity relationships of various drug candidates. Its unique structural features enable researchers to investigate the effects of fluorination and piperidine ring on the biological activity and pharmacokinetic properties of the synthesized compounds.
Used in Chemical Reactions:
5,5-Difluoro-1,3-piperidinedicarboxylic acid tert-butyl ester is used as a reactant in various chemical reactions, such as esterification, amidation, and acylation, due to the presence of the carboxylic acid functionality. The tert-butyl ester group provides protection to the carboxylic acid, allowing for selective reactions and easier manipulation during the synthesis process.
Check Digit Verification of cas no
The CAS Registry Mumber 1255666-86-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,5,6,6 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1255666-86:
(9*1)+(8*2)+(7*5)+(6*5)+(5*6)+(4*6)+(3*6)+(2*8)+(1*6)=184
184 % 10 = 4
So 1255666-86-4 is a valid CAS Registry Number.
1255666-86-4Relevant academic research and scientific papers
NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND
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Paragraph 0411-0413, (2016/08/29)
The present invention provides a compound represented by the following formula (I) or its pharmaceutically acceptable salt: [wherein, R1 represents optionally substituted C1-4 alkyl, n shows integer of 1 to 4, R2 represents optionally substituted C1-4 alkyl or hydrogen atom, R3 represents optionally substituted C1-4 alkyl, R4a, R4b, R4c, and R4d, similarly or differently, represent optionally substituted C6-14 aryl, optionally substituted C1-4 alkyl, or hydrogen atom and the like, A represents optionally substituted C6-14 aryl or optionally substituted 5 to 11 membered heteroaryl].
SUBSTITUTED [1,2,4] TRIAZOLO [1,5-A] PYRIMIDIN-7-YL COMPOUNDS AS PDE2 INHIBITORS
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Page/Page column 53-54, (2015/11/10)
The invention provides a chemical entity of Formula (I): wherein R1, R2, X, Y and Z have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of
