1255772-46-3

Upstream product

• 6479-18-1 1-methyl-2(1H)-quinoxalinone 
• 106-40-1 4-bromo-aniline 
• 5467-74-3 4-Bromophenylboronic acid 
• 1712-82-9 p-bromodibenzoyl peroxide 
• 21453-02-1 3-(4-bromophenyl)quinoxalin-2(1H)-one 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 1255772-68-9 3-(4-bromophenyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one 

Relevant academic research and scientific papers

Direct decarboxylative C[sbnd]H 3-arylation of quinoxalin-2(H)-ones with aryl acyl peroxides leading to 3-arylquinoxalin-2(1H)-ones

A facile and direct decarboxylative C[sbnd]H 3-arylation of quinoxalin-2(H)-ones with aryl acyl peroxides has been developed for the synthesis of 3-arylquinoxalin-2(1H)-ones under simple heating conditions. The present methodology provides a simple and highly efficient approach to various 3-arylquinoxalin-2(1H)-ones in high yields without the use of any catalyst and additives.

Mild and Direct C-H Arylation of Quinoxalin-2(1 H)-ones with Aryldiazonium Salts under Metal-Free Conditions

A mild and direct C-H arylation of quinoxazolin-2(1 H)-ones with aryldiazonium salts has been developed. A wide variety of 3-arylquinoxazolin-2(1 H)-ones were synthesized in up to 92% yield at room temperature under metal-free conditions. This strategy tolerates a wide range of functional groups and shows environmental friendliness and practicality.

Visible-light-induced C[sbnd]H arylation of quinoxalin-2(1H)-ones in H2O

An efficient visible-light-induced C[sbnd]H arylation of quinoxalin-2(1H)-ones in H2O is developed, which has the advantages of mild reaction conditions, environmental friendliness and good functional group tolerance. This strategy provides a s

Aryl acyl peroxides for visible-light induced decarboxylative arylation of quinoxalin-2(1: H)-ones under additive-, metal catalyst-, and external photosensitizer-free and ambient conditions

Aryl radicals were generated for the first time from cheap and easily available aryl acyl peroxides in eco-friendly ethyl acetate under ambient conditions and visible-light illumination in the absence of any additive, metal catalyst, or external photosensitizer. The present arylation of quinoxalin-2(1H)-ones was chemo- and regioselective, and provided good access to various 3-arylquinoxalin-2(1H)-ones. This journal is

Direct C-H arylation of quinoxalinones with aryl acylperoxides under catalyst-free condition

A simple and novel method for the direct C-H arylation of quinoxalinones with aryl acylperoxides has been developed. This reaction proceeded smoothly through a radical process under catalyst-free condition, giving the target products in moderate good yields. Such strategy provides a simple and green alternative for the synthesis of 3-arylquinoxalinones.

K2S2O8 mediated C-3 arylation of quinoxalin-2(1H)-ones under metal-, photocatalyst- And light-free conditions

Two facile and effective C-3 arylation protocols of quinoxalin-2(1H)-ones with arylhydrazines and aryl boronic acids respectively via free radical cross-coupling reactions under metal-, photocatalyst- and light-free conditions have been unveiled. K2

Photocatalytic synthesis method of 3-aryl-N-methylquinoxalin-2(1H)-one compound

The invention discloses a photocatalytic synthesis method of a 3-aryl-N-methylquinoxalin-2(1H)-one compound, wherein the method comprises the steps: carrying out one-pot reaction on an N-methylquinoxalin-2(1H)-one compound and an aryl formyl peroxide comp

A inhibitors and synthetic method of derivative thereof (by machine translation)

The invention discloses a inhibitors and synthetic method of derivative thereof: in formula I the quinoxaline - 2 - formaldehyde as the initiator, dissolved in organic solvent, in the oxygen atmosphere, under the action of the reagent in the format, for 0

Transition-Metal-Free Direct C-H Arylation of Quinoxalin-2(1H)-ones with Diaryliodonium Salts at Room Temperature

A method of synthesizing 3-arylquinoxalin-2(1H)-ones using diaryliodonium tetrafluoroborates under mild conditions is described. This protocol has a wide substrate scope and enables direct C-H functionalization. The synthetic potential of this coupling was explored using a range of readily accessible diaryliodonium salts and quinoxalin-2(1H)-ones.

Transition Metal-Free Direct C-3 Arylation of Quinoxalin-2(1H)-ones with Arylamines under Mild Conditions

A transition metal-free direct C-3 arylation of quinoxalin-2(1H)-ones with arylamines has been explored. This reaction proceeded smoothly through a radical process under mild conditions and produced the desired arylation products in good yields. The reactions proceeded efficiently with a broad range of substrates and functional group tolerance. (Figure presented.).