28746-20-5

Basic information

• Product Name: Benzaldehyde, 3-(methoxymethyl)-
• CAS NO: 28746-20-5
• Molecular Formula: C9H10O2
• Molecular Weight: 150.177
• Mol File: 28746-20-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 3-(methoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3-(methoxymethyl)-(28746-20-5)
• EPA Substance Registry System: Benzaldehyde, 3-(methoxymethyl)-(28746-20-5)

Safety Data

• Hazardous Substances Data: 28746-20-5(Hazardous Substances Data)

Upstream product

• 140639-94-7 2-(3'-hydroxymethyl)phenyl-1,3-dioxolane 
• 74-88-4 methyl iodide 
• 124-41-4 sodium methylate 
• 82072-23-9 3-(bromomethyl)benzaldehyde 
• 64407-07-4 3-(chloromethyl)benzonitrile 
• 125604-03-7 1-(bromomethyl)-3-(methoxymethyl)benzene 
• 1515-86-2 (3-Cyanophenyl)methyl methyl ether 
• 77072-00-5 3-chloromethylbenzaldehyde 
• 626-15-3 1,3-bis-(bromomethyl)benzene 
• 22072-45-3 1,3-di-(methoxy-methyl)benzene 

Downstream Products

• 1201634-96-9 C₂₄H₂₈O₃ 
• 265329-24-6 3-[1-(3-Methoxymethylbenzyl)piperidin-4-yl]-4-(4-chlorophenyl)-3,4-dihydro-2(1H)-quinazolinone 
• 796870-90-1 methyl 2-azido-3-(3-methoxymethylphenyl)acrylate 
• 28817-02-9 {3-[(Z)-2-(3-Hydroxymethyl-phenyl)-vinyl]-phenyl}-methanol 
• 28817-07-4 3,3'-Bis(methoxymethyl)-2-methyl-trans-stilben 
• 28817-08-5 3,3'-Bis(acetoxymethyl)-2-methyl-cis-stilben 
• 28817-03-0 (Z)-3,3'-Bis(brommethyl)stilben 
• 15323-33-8 3,3'-Bis(acetoxymethyl)-trans-stilben 
• 72985-28-5 3,5'-Bis(methoxymethyl)-2'-methyldeoxybenzoin trimethylene dithioketal 
• 72985-00-3 3,5'-Bis(brommethyl)-2'-methyldeoxybenzoin trimethylene dithioketal 
• 28816-99-1 3,3'-Bis(hydroxymethyl)-cis-stilben 
• 28816-99-1 3,3'-Bis(methoxymethyl)-trans-stilben 
• 15323-31-6 3,3'-Bis(bromomethyl)-trans-stilben 
• 28817-04-1 3,3'-Bis(methoxymethyl)-2-methyl-cis-stilben 

Relevant articles and documents

BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF

The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

CBI analogues of the duocarmycins and CC-1065

An extensive series of CBI analogues of the duocarmycins and CC-1065 exploring substituent effects within the first indole DNA binding subunit is detailed. In general, substitution at the indole C5 position led to cytotoxic potency enhancements that can be ≧1000-fold providing simplified analogues containing a single DNA binding subunit that are more potent (IC50=2-3 pM) than CBI-TMI, duocarmycin SA, or CC-1065. The increases in cytotoxicity correlate well with accompanying increases in the rate and efficiency of DNA alkylation. This effect is more pronounced with the CBI versus DSA or CPI based analogues. Moreover, this effect is largely insensitive to the electronic character of the C5 substituent but is sensitive to the size, rigid length, and shape (sp, sp2, sp3 hybridization) of this substituent consistent with expectation that the impact is due simply to its presence.

Quantitative structure-selectivity relationships. Comparison of the inhibition of Escherichia coli and bovine liver dihydrofolate reductase by 5-(substituted-benzyl)-2,4-diaminopyrimidines

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