125607-09-2Relevant academic research and scientific papers
A SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELL NUCLEI
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Page/Page column 90-91, (2008/06/13)
A novel class of oligomeric compounds designed for forming conjugates with biologically active substances and delivering these substances to a desired bodily target are disclosed. Nove1 conjugates of biologically active moities and such oligomeric compounds, pharmaceutical compositions containing such conjugates, and uses thereof as delivery systems for delivering the biologically active substances to a desired target are further disclosed. Processes of preparing the conjugates and the oligomeric compounds and novel intermediates designed for and used in these processes are also disclosed.
Binding of aminoglycoside antibiotics with modified A-site 16S rRNA construct containing non-nucleotide linkers
Tok, Jeffrey B.-H.,Wong, Wilson,Baboolal, Nyla
, p. 365 - 370 (2007/10/03)
The design and synthesis of synthetically modified cyclic A-site 16S rRNA construct is reported. The binding characteristics of several members of the aminoglycoside antibiotics with this novel class of synthetically modified A-site 16S rRNA constructs we
