1256161-69-9

Basic information

• Product Name: methyl (4R)-4-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylate
• Synonyms: methyl (4R)-4-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylate
• CAS NO: 1256161-69-9
• Molecular Weight: 253.685
• Mol File: 1256161-69-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (4R)-4-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (4R)-4-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylate(1256161-69-9)
• EPA Substance Registry System: methyl (4R)-4-(4-chlorophenyl)-2-oxopyrrolidine-3-carboxylate(1256161-69-9)

Safety Data

• Hazardous Substances Data: 1256161-69-9(Hazardous Substances Data)

Upstream product

• 360072-54-4 methyl 2-carbomethoxy-4-nitro-3-(4-chloro-phenyl)-butyrate 
• 101671-01-6 1-nitro-2-(4-chlorophenyl)ethylene 
• 761434-42-8 (R)(-)-2-[1-(4-chlorophenyl)-2-nitroethyl]malonic acid dimethyl ester 

Downstream Products

• 123632-35-9 (R)-(-)-4-(4-chlorophenyl)pyrrolidin-2-one 
• 63701-55-3 (R)-(-)-baclofen hydrochloride 
• 834917-64-5 (R)-4-(4-Chloro-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid 

Relevant articles and documents

Squaramide-Catalyzed Michael Addition as a Key Step for the Direct Synthesis of GABAergic Drugs

Enantioselective organocatalytic Michael additions serve as the key step in syntheses of chiral drugs based on γ-aminobutyric acid. The applicability of various squaramide catalysts for these Michael-type reactions has been assessed. Very good results in