1257244-86-2

Basic information

• Product Name: sodium N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}dithiocarbamate
• CAS NO: 1257244-86-2
• Molecular Weight: 361.508
• Mol File: 1257244-86-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: sodium N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}dithiocarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: sodium N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}dithiocarbamate(1257244-86-2)
• EPA Substance Registry System: sodium N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}dithiocarbamate(1257244-86-2)

Safety Data

• Hazardous Substances Data: 1257244-86-2(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 21103-33-3 4-[4-(2-methoxyphenyl)piperazin-1-yl]butylamine 
• 102392-05-2 2-(4-(4-(2-methoxyphenyl)-piperazin-1-yl)butyl)-isoindole-1,3-dione 

Relevant articles and documents

Synthesis of several MPP derivatives for 99mTc-labelling and evaluated as potential 5-HT1A receptor imaging agents

The (2-methoxyphenyl) piperazine (MPP) was selected as the functional group and conjugated to dithiocarbamate through different spacers. A series of new MPP derivatives (MPPnDTC, n = 2-6) were synthesized and radiolabelled with 99mTc-nitrido core or 99mTc-tricarboxyl core as potential 5-HT1A receptor imaging agents. All the six 99mTc-labelled complexes were lipophilic and neutral. Biodistribution results showed that those radiotracers had moderate initial brain and hippocampus uptake. There have no significant relation was observed between the biological properties of these tracers with the length of its carbon chain. The radioactivity concentrations of hippocampus of 99mTcN-MPP2DTC, 99mTcN-MPP3DTC, 99mTcN-MPP4DTC, 99mTcN-MPP5DTC, 99mTcN-MPP6DTC and 99mTc(CO)3-MPP3DTC at 2 min post-injection time (p.i.) were 0.43, 1.15, 0.99, 1.04, 1.13 and 0.83 %ID/g, respectively.