1257629-83-6

Basic information

• Product Name: C₁₄H₁₃F₃N₂O₃
• CAS NO: 1257629-83-6
• Molecular Weight: 314.264
• Mol File: 1257629-83-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₃F₃N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₃F₃N₂O₃(1257629-83-6)
• EPA Substance Registry System: C₁₄H₁₃F₃N₂O₃(1257629-83-6)

Safety Data

• Hazardous Substances Data: 1257629-83-6(Hazardous Substances Data)

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 84654-29-5 5-(bromomethyl)-3-isoxazolecarboxylic acid ethyl ester 

Downstream Products

• 1257629-92-7 C₁₅H₁₅F₃N₂O₃ 

Relevant articles and documents

NOC chemistry for tuberculosis - Further investigations on the structure-activity relationships of antitubercular isoxazole-3-carboxylic acid ester derivatives

NOC, NOC! Who's there? We have expanded the body of structure-activity relationships (SAR) regarding the 3-isoxazolecarboxylic acid ethyl esters by the design and synthesis of 5-aryl- and 5-[(N-aryl)amino]methyl analogues. Compounds were active against Mycobacterium tuberculosis (Mtb) at sub-micromolar concentrations and, for selected compounds, no toxicity was observed on Vero cells.