125962-61-0

Basic information

• Product Name: 8-(4-BROMOPHENYL)-1,4-DIOXASPIRO[4,5]DECANE
• Synonyms: ALLICHEM 10143;8-(4-BROMOPHENYL)-1,4-DIOXASPIRO[4,5]DECANE;8-(4-BROMOPHENYL)-1,4-DIOXASPRIO[4,5]DECANE
• CAS NO: 125962-61-0
• Molecular Formula: C₁₄H₁₇BrO₂
• Molecular Weight: 297.19
• Mol File: 125962-61-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 376.9°Cat760mmHg
• Flash Point: 164.4°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: 8-(4-BROMOPHENYL)-1,4-DIOXASPIRO[4,5]DECANE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(4-BROMOPHENYL)-1,4-DIOXASPIRO[4,5]DECANE(125962-61-0)
• EPA Substance Registry System: 8-(4-BROMOPHENYL)-1,4-DIOXASPIRO[4,5]DECANE(125962-61-0)

Safety Data

• Hazardous Substances Data: 125962-61-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H17BrO2/c15-13-3-1-11(2-4-13)12-5-7-14(8-6-12)16-9-10-17-14/h1-4,12H,5-10H2

Upstream product

• 125962-59-6 4-Hydroxy-4-(p-bromophenyl)cyclohexanone ethylene ketal 
• 125962-60-9 8-(4-bromophenyl)-1,4-dioxaspiro[4.5]dec-7-ene 
• 155472-39-2 4'-bromo-2,5-dihydro-[1,1'-biphenyl]-4(3H)-one 
• 107-21-1 ethylene glycol 
• 84892-43-3 4-(p-bromophenyl)-cyclohexanone 

Downstream Products

• 84892-43-3 4-(p-bromophenyl)-cyclohexanone 
• 155472-45-0 (+/-)-1-<(p-Cyanophenyl)methylene>-4-<4'-(phenylethynyl)phenyl>cyclohexane 

Relevant articles and documents

Cobalt-Catalyzed Desymmetric Isomerization of Exocyclic Olefins

Chiral cyclic olefins, 1-methylcyclohexenes, are versatile building blocks for the synthesis of pharmaceuticals and natural products. Despite the prevalence of these structural motifs, the development of efficient synthetic methods remains an unmet challenge. Herein we report a novel desymmetric isomerization of exocyclic olefins using a series of newly designed chiral cobalt catalysts, which enables a straightforward construction of chiral 1-methylcyclohexenes with diversified functionalities. The synthetic utility of this methodology is highlighted by a concise and enantioselective synthesis of a natural product, β-bisabolene. The versatility of the reaction products is further demonstrated by multifarious derivatizations.