126014-45-7Relevant academic research and scientific papers
Highly regio- and stereoselective synthesis of 1,3-enynes from unactivated ethylenes via palladium-catalyzed cross-coupling
Wen, Yanmei,Wang, Azhong,Jiang, Huanfeng,Zhu, Shifa,Huang, Liangbin
supporting information; experimental part, p. 5736 - 5739 (2011/12/03)
An efficient procedure for regio- and stereoselective synthesis of a series of conjugated enynes by a simple Pd-catalyzed cross-coupling reaction of unactivated ethylenes and ethynyl bromide has been developed. The reaction proceeds smoothly in DMF to give the corresponding products in good to excellent yields. The protocol can tolerate a broad range of functional groups on the substrates.
Iron-catalyzed enyne cross-coupling reaction
Hatakeyama, Takuji,Yoshimoto, Yuya,Gabriel, Toma,Nakamura, Masaharu
supporting information; experimental part, p. 5341 - 5344 (2009/06/06)
(Chemical Equation Presented) In the presence of 0.5-1 mol % of FeCl 3 with lithium bromide as a crucial additive, alkynyl Grignard reagents, prepared from the corresponding alkynes and methylmagnesium bromide, react with alkenyl bromides or triflates to give the corresponding conjugated enynes in high to excellent yields. The reaction shows wide applicability to various terminal alkynes and alkenyl electrophiles.
Dialkyltitanium-mediated titanation of conjugated 1,3-butadiynes and its coupling reactions with aldehydes: a facile synthesis of stereodefined enynes and trans-enynols
Chen, Jingjin,Liu, Yuanhong
supporting information; experimental part, p. 6655 - 6658 (2009/04/07)
A highly efficient and convenient method for the selective titanation of 1,3-butadiynes using Ti(OiPr)4/nBuLi reagent has been developed. The method provided a facile synthesis of enynes and trans-enynols in a well-stereod
Site-selective mono-titanation of conjugated diynes with a Ti(II) alkoxide reagent. Concise preparation of stereo-defined enynes and dienynes
Delas, Christophe,Urabe, Hirokazu,Sato, Fumie
, p. 272 - 273 (2007/10/03)
Conjugated diynes underwent selective mono-titanation with a Ti(II) reagent to give 1:1 diyne - titanium alkoxide complexes, which reacted with proton, aldehyde, and another acetylene to give stereo-defined enynes, enynols, and dienynes.
An alternative general preparation of 2-alkyl-1-benzostannepines and their conversion into 1-benzostibepines and 1-benzoborepines via a tin-metal exchange
Sashida, Haruki,Kuroda, Atsuhiro
, p. 1965 - 1969 (2007/10/03)
The 2-alkyl-1-benzostannepines 4a-g were prepared by the intramolecular hydrostannation of the tin intermediates 3 to an acetylenic moiety in one pot from (Z)-1-(o-bromophenyl)but-1-en-3-ynes 1. The obtained stannepines 4 were easily converted into the 1-benzostibepines 9, 10, 11, 12 and the 1-benzoborepines 14, 15 by tin-antimony and t/n-boron exchange reactions in moderate to good yields, respectively. The 1-benzoborepines 14 and 15 are hitherto unknown heterocyclic ring systems.
AN ALTERNATIVE METHOD FOR THE STEREOSPECIFIC SYNTHESIS OF CONJUGATED ALKENES VIA THE COPPER(I) IODIDE ASSISTED CROSS-COUPLING REACTION OF 1-ALKYNES WITH HALOALKENES
Ogawa, Takuji,Kusume, Kumiko,Tanaka, Miyuki,Hayami, Kazuo,Suzuki, Hitomi
, p. 2199 - 2108 (2007/10/02)
Conjugated alkenynes were prepared stereospecifically in moderate to good yields by heating haloalkenes with 1-alkynes in the presence of copper(I) iodide in hexamethylphosphoric triamide (HMPA).
