42599-24-6

Basic information

• Product Name: Benzene, (2-iodoethenyl)-, (E)-
• CAS NO: 42599-24-6
• Molecular Formula: C8H7I
• Molecular Weight: 230.048
• Mol File: 42599-24-6.mol
• Article Data: 74

Chemical Properties

• Boiling Point: 101 °C(Press: 4 Torr)
• Density: 1.733±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzene, (2-iodoethenyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (2-iodoethenyl)-, (E)-(42599-24-6)
• EPA Substance Registry System: Benzene, (2-iodoethenyl)-, (E)-(42599-24-6)

Safety Data

• Hazardous Substances Data: 42599-24-6(Hazardous Substances Data)

Upstream product

• 588-72-7 [(E)-2-bromoethenyl]benzene 
• 75-47-8 iodoform 
• 100-52-7 benzaldehyde 
• 140-10-3 (E)-3-phenylacrylic acid 
• 1419285-44-1 1-phenyl-2-(tribenzylstannyl)ethene 
• 100-42-5 styrene 
• 536-74-3 phenylacetylene 
• 1483-82-5 phenylethynyl chloride 
• 16932-44-8 2-iodo-1,3-dimethoxybenzene 
• 1206-29-7 triethyl(styryl)silane 
• 83947-56-2 4,4,5,5-tetramethyl-2-((E)-styryl)-[1,3,2]dioxaborolane 
• 75-11-6 diiodomethane 
• 100-39-0 benzyl bromide 
• 109317-98-8 2-phenylethane-1,1-diyl bis(trifluoromethanesulfonate) 

Downstream Products

• 119946-59-7 2-(2'-trans-styryl)-2,5-dihydrofuran 
• 65136-45-0 2-ethyl-1-methyl-1H-indole 
• 114701-81-4 (E)-trimethyl(4-phenyl-1,3-butadien-2-yl)silane 
• 84247-82-5 (E)-1-pentyl-5-trimethylsilyl-1,3-pentadiene 
• 135508-11-1 (E)-12-Oxo-14-phenyl-13-tetradecenonitrile 
• 27044-91-3 4-phenyl-3,4,7,8-tetrahydro-2H-chromene-2,5(6H)-dione 
• 40596-14-3 anti-3-phenyl-4-hydroxy-1-pentene 
• 119946-56-4 (E)-[2-(cyclopent-2-en-1-yl)ethen-1-yl]benzene 
• 130274-38-3 (E)-1,3-bis(trimethylsilyl)-6-phenylfulvene 
• 16939-57-4 (E)-buta-1,3-dienylbenzene 
• 70960-88-2 trimethyl ((1E,3E)-4-phenylbuta-1,3-dien-1-yl)silane 
• 30154-21-3 (4E)-5-phenylpent-4-enenitrile 
• 144270-76-8 (Z)-5-phenylpent-4-enenitrile 
• 111122-65-7 (E,E)-4-phenyl-1-phenylseleno-1,3-butadiene 

Relevant articles and documents

Asymmetric Synthesis of γ-Lactams Containing α,β-Contiguous Stereocenters via Pd(II)-Catalyzed Cascade Methylene C(sp3)-H Alkenylation/Aza-Wacker Cyclization

γ-Lactam containing α,β-contiguous stereogenic centers stands out as a pivotal motif in various bioactive compounds, while its efficient synthesis still needs to be enhanced. Herein, an asymmetric C-H activation strategy for accessing α,β-stereospecific γ-lactams in good yields (≤79%) with high enantio- and diastereoselectivities (≤96% ee and >20:1 dr) was described, which serves as an effective supplement to the existing strategies.

Stereostructure Clarifying Total Synthesis of the (Polyenoyl)tetramic Acid Militarinone B. A Highly Acid-Labile N-Protecting Group for Amides ?

The 5S, 8′R, and 10′R configurations of militarinone B (3), which is a natural product from Paecilomyces militaris, should equal those in its biosynthetic precursor, militarinone C. The configuration at C-1′ emerged from syntheses of the militarinone B candidates 1′′S- and 1′′R-(5S,8′R,10′R)-3 from the building blocks 9, 11, 14, and 15a while introducing TMB as a more acid-labile N-protecting group for β-ketoamides than DMB. Comparisons of 1′′S- and 1′′R-(5S,8′R,10′R)-3 with natural militarinone B (3; reisolated from Nature) revealed identity versus distinctness.

Copper-Photocatalyzed Hydrosilylation of Alkynes and Alkenes under Continuous Flow

Herein, the photocatalytic hydrosilylation of alkynes and alkenes under continuous flow conditions is described. By using 0.2 mol % of the developed [Cu(dmp)(XantphosTEPD)]PF6 under blue LEDs irradiation, a large panel of alkenes and alkynes was hydrosilylated in good to excellent yields with a large functional group tolerance. The mechanism of the reaction was studied, and a plausible scenario was suggested.