126078-18-0

Basic information

• Product Name: 1-Propanone, 2-methyl-1-phenyl-2-(phenylsulfonyl)-
• CAS NO: 126078-18-0
• Molecular Formula: C16H16O3S
• Molecular Weight: 288.367
• Mol File: 126078-18-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 2-methyl-1-phenyl-2-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 2-methyl-1-phenyl-2-(phenylsulfonyl)-(126078-18-0)
• EPA Substance Registry System: 1-Propanone, 2-methyl-1-phenyl-2-(phenylsulfonyl)-(126078-18-0)

Safety Data

• Hazardous Substances Data: 126078-18-0(Hazardous Substances Data)

Upstream product

• 16722-50-2 phenylsulphinate anion 
• 7473-99-6 α-chloroisobutyrophenone 
• 108-98-5 thiophenol 
• 4238-09-9 phenyl isopropyl sulfone 
• 3019-20-3 isopropylthiobenzene 
• 91787-39-2 trimethyl<1-(phenylsulphonyl)ethyl>silane 
• 98-88-4 benzoyl chloride 
• 137345-35-8 (1-Benzenesulfonyl-1-methyl-ethyl)-trimethyl-stannane 

Downstream Products

• 7473-98-5 2-hydroxy-2-methylpropiophenone 
• 611-70-1 phenyl isopropyl ketone 
• 1394206-54-2 2-methyl-1-phenyl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)propan-1-one 

Relevant articles and documents

Scope and limitations in the use of α-silyl and α-stannyl sulfones as latent α-sulfonyl anions

Three methods for the regeneration of α-sulfonyl anions from α-silyl sulfones and α-stannyl sulfones are investigated. These methods include: (1) treatment of α-silyl sulfones with electrophiles (aldehydes and acid halides) in the presence of fluoride ion; (2) reaction of α-silyl sulfones with n-butyllithium which produces an α-silyl anion via a migration of the -SiMe3 group from the α-position to the ortho-position of the phenyl sulfones; and (3) direct transmetalation of α-stannyl sulfone by treatment with n-butyllithium. The addition of cerium [III] chloride is shown to substantially decrease enolization problems associated with addition of α-sulfonyl anions to carbonyl compounds bearing enolizable protons.