1262396-58-6

Basic information

• Product Name: (1S)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid
• Synonyms: (1S)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid
• CAS NO: 1262396-58-6
• Molecular Weight: 356.465
• Mol File: 1262396-58-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1S)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid(1262396-58-6)
• EPA Substance Registry System: (1S)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid(1262396-58-6)

Safety Data

• Hazardous Substances Data: 1262396-58-6(Hazardous Substances Data)

Upstream product

• 16771-84-9 1-cyclohexyl-4-piperidinone 
• 108-31-6 maleic anhydride 
• 1262396-56-4 1-cyclohexyl-N-[(1S)-1-(furan-2-yl)ethyl]piperidin-4-amine 

Downstream Products

• 1262395-13-0 NMS-P₅₁₅ 

Relevant articles and documents

3-0X0-2, 3, -DIHYDRO-LH-ISOINDOLE-4-CARBOXAMIDES WITH SELECTIVE PARP-1 INHIBITION

There are provided substituted 3 -oxo - 2, 3 -dihydro- 1H-isoindole-4-carboxamide derivatives (I) which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of this invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.