1262887-44-4

Basic information

• Product Name: C₁₈H₂₃N₃O₇
• Synonyms: C₁₈H₂₃N₃O₇
• CAS NO: 1262887-44-4
• Molecular Weight: 393.397
• Mol File: 1262887-44-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₃N₃O₇(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₃N₃O₇(1262887-44-4)
• EPA Substance Registry System: C₁₈H₂₃N₃O₇(1262887-44-4)

Safety Data

• Hazardous Substances Data: 1262887-44-4(Hazardous Substances Data)

Upstream product

• 635683-64-6 1,6:2,3-bisanhydro-4-O-p-methoxybenzyl-β-D-glucopyranose 
• 635683-65-7 1,6-anhydro-2-azido-2-deoxy-4-O-p-methoxybenzyl-β-D-glucopyranose 
• 67-56-1 methanol 
• 100-39-0 benzyl bromide 
• 139437-39-1 1,6-anhydro-2-deoxy-2-iodo-β-D-glucopyranose 
• 13265-84-4 D-glucal 
• 2873-29-2 D-glucal triacetate 
• 134221-42-4 1,6-anhydro-2-azido-3-O-benzyl-2-deoxy-4-O-(p-methoxybenzyl)-β-D-glucopyranose 

Downstream Products

• 501088-17-1 methyl 2-azido-6-O-benzoyl-3-O-benzyl-2-deoxy-α-D-glucopyranoside 
• 175978-55-9 methyl 2-azido-3-O-benzyl-2-deoxy-α-D-glucopyranoside 

Relevant articles and documents

AN EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM

The present invention relates to a process for the synthesis of the Factor Xa anticoagulent Fondaparinux and related compounds. The invention relates, in addition, to efficient and scalable processes for the synthesis of various intermediates useful in the synthesis of Fondaparinux and related compounds.

PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF

Processes for the synthesis of the Factor Xa anticoagulent Fondaparinux, and related compounds are described. Also described are protected pentasaccharide intermediates as well as efficient and scalable processes for the industrial scale production of Fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions.