1263796-97-9Relevant academic research and scientific papers
Three-component reaction: Synthesis, characterization, and biological study of some fused bridgehead nitrogen heterocyclic systems containing 4-methylthiophenyl moiety
Manjunatha,Poojary, Boja,Lobo, Prajwal L.,Kumari, N. Suchetha,Anoop
, p. 526 - 532 (2011/05/15)
Several substituted thiazolo-[3,2-b]-1,2,4-triazole derivatives 4 were synthesized by a one-pot, three-component reaction of 3-(4-methylthiobenzyl)-1, 2,4-triazole-5-thiol 3, substituted 5-aryl-furan-2-carboxaldehydes/substituted aromatic aldehydes, and monochloroacetic acid in acetic acid using acetic anhydride and anhydrous sodium acetate. Compound 3 was obtained from 4-methylthiophenyl acetic acid by esterification followed by hydrazinolysis. All structures of the newly synthesized compounds were elucidated by elemental analysis and spectral data. The newly synthesized compounds were also screened for their antimicrobial and anti-inflammatory activities. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright Taylor & Francis Group, LLC.
Synthesis of some fused triazole derivatives containing 4-isobutylphenylethyl and 4-methylthiophenyl moieties
Kumsi, Manjunatha,Poojary, Boja,Lobo, Prajwal L.,Fernandes, Jennifer,Chikkanna, Chandrashekhar
experimental part, p. 1353 - 1358 (2011/01/08)
A series of substituted [1,3]thiazolo[3,2-b][1,2,4]triazole derivatives 4 were synthesized in good yield by condensing 2-substituted-1,2,4-triazole-5- thiols 3 with various N-aryl-maleimides in acetic acid media. All structures of the newly synthesized compounds were elucidated by elemental analyses and spectral data.
