126403-71-2

Basic information

• Product Name: Zinc, bromo(4-methylphenyl)-
• CAS NO: 126403-71-2
• Molecular Formula: C7H7BrZn
• Molecular Weight: 236.427
• Mol File: 126403-71-2.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Zinc, bromo(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, bromo(4-methylphenyl)-(126403-71-2)
• EPA Substance Registry System: Zinc, bromo(4-methylphenyl)-(126403-71-2)

Safety Data

• Hazardous Substances Data: 126403-71-2(Hazardous Substances Data)

Upstream product

• 7646-85-7 zinc(II) chloride 
• 106-38-7 para-bromotoluene 
• 7699-45-8 zinc dibromide 
• 7440-66-6 zinc 
• 4294-57-9 para-methylphenylmagnesium bromide 

Downstream Products

• 90252-90-7 3-(4-tolyl)-3-butenoic acid 
• 5184-70-3 1-bromo-4-tosylbenzene 
• 640-57-3 phenyltolylsulfone 
• 1198348-26-3 5-fluoro-2-(4-methylphenyl)pyridine 
• 5395-79-9 4'-methyl-4-chlorobenzophenone 
• 134-84-9 4-Methylbenzophenone 
• 611-97-2 bis(p-methylphenyl)-methanone 
• 613-33-2 (4,4'-dimethyl-1,1'-biphenyl) 
• 1283129-19-0 2,3,4,6-tetra-O-pivaloyl 1-(4-tolyl)-1-deoxy-β-D-glucopyranose 
• 1452488-99-1 methyl (E)-3-(2-(N-(2-(p-tolyl)hexyl)sulfamoyl)phenyl)acrylate 
• 1452488-98-0 methyl (E)-3-(2-(N-(1-(p-tolyl)hexan-2-yl)sulfamoyl)phenyl)acrylate 
• 1452489-61-0 C₂₃H₂₉NO₄S 
• 1452489-62-1 methyl (E)-3-(2-(N-((E)-6-(3-phenylpropoxy)-5-(p-tolyl)hex-2-en-1-yl)sulfamoyl)phenyl)acrylate 
• 1452489-63-2 methyl (E)-3-(2-(N-((E)-4-(4-methylbenzyl)-5-(3-phenylpropoxy)pent-2-en-1-yl)sulfamoyl)phenyl)acrylate 

Relevant articles and documents

Sequential Organozinc Formation and Negishi Cross-Coupling of Amides Catalysed by Cobalt Salt

Herein, a cobalt-catalysed Negishi-type cross-coupling of amide derivatives is described. Apart from being the first example of cobalt-catalysed Negishi-type coupling of amides, the process described employs a unique, simple, and cheap catalytic system to perform both the organozinc formation and the Negishi-type coupling. Indeed, the same cobalt(II) bromide salt used to form the arylzinc species from aryl bromides is then re-used to perform the cross coupling of this resulting arylzinc with N-benzoyl glutarimides at room temperature. The main advantages of the reaction presented are its robustness and ease of use. Indeed, the reactions of organozinc formation and Negishi-type coupling are performed without precautions toward water or oxygen. (Figure presented.).

One-pot synthesis of aryl sulfones from organometallic reagents and iodonium salts

A transition-metal-free arylation of lithium, magnesium, and zinc sulfinates with diaryliodonium salts is described. The sulfinic acid salts were prepared from the reaction of the corresponding organometallic reagents and sulfur dioxide. Combination of the three single steps (preparation of the organometallic compound, sulfinate formation, and arylation) leads to a one-pot sequence for the synthesis of aryl sulfones from simple starting materials. The chemoselectivity of unsymmetrical diaryliodonium salts has been investigated. Potential and limitations of this method will be discussed.

Nickel-catalyzed enantioselective arylation of pyridinium ions: Harnessing an iminium ion activation mode

A nickel for your thoughts.?? An enantioselective nickel-catalyzed cross-coupling between N-acylpyridinium salts and organozinc reagents is reported. The catalytic system, which is comprised of an air-stable NiII source and a chiral phosphoramidite ligand, affords 2-substituted-2,3-dihydro-4-pyridones with up to >99 % ee. Copyright