126541-65-9Relevant academic research and scientific papers
aminoalkylbenzotriazoles: Reagents for the aminoalkylation of electron rich heterocycles
Katritzky,Yang,Lam
, p. 4971 - 4978 (1992)
Secondary and tertiary aminoalkylbenzotriazoles react with pyrrole, indole, their N-methyl analogs and with 2-methylfuran under mild reaction conditions in the presence of a Lewis acid to afford selectively the corresponding secondary or tertiary amines.
HALO-SUBSTITUTED PYRIMIDODIAZEPINES
-
Page/Page column 6, (2009/12/28)
The present invention provides PLK1 inhibitor compounds of formula I: useful in the treatment or control of cell proliferative disorders, particularly oncological disorders. These compounds and formulations containing such compounds may be useful in the treatment or control of solid tumors, such as, for example, breast, colon, lung and prostate tumors and other oncological diseases such as non-Hodgkin's lymphomas. Also provided are intermediate compounds useful in the synthesis of compounds of formula I.
The N-Substitution of Aliphatic Primary Amines via 1-benzotriazoles: Preparation of Secondary Amines
Katritzky, Alan R.,Glen, Noble,Pilarski, Boguslaw,Harris, Philip
, p. 1443 - 1446 (2007/10/02)
A new method has been developed for the selective conversion of primary aliphatic amines into unsymmetrical secondary amines by Grignard reaction of 1-benzotriazoles 1.This method employs simple procedures and mild conditions, and is specific in that onyl monoalkylation of the primary amines results.
Reactions of Benzotriazole with Formaldehyde and Aliphatic Primary Amines: Selective Formation of 1:1:1, of 2:2:1, and of 2:3:2 Adducts and a Study of their Reactions with Nucleophiles
Katritzky, Alan R.,Pilarski, Boguslaw,Urogdi, Laszlo
, p. 541 - 547 (2007/10/02)
Benzotriazole (BtH) reacts easily with aliphatic primary amines and formaldehyde in aqueous media to give one or more of three types of product: (i) (BtCCH2)2NR (5), (ii) (BtCH2NR)2CH2 (6), and/or (iii) BtCH2NHR (7).The product formed depends on the molar
