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Althiomycin is a naturally occurring thiopeptide antibiotic derived from the bacterium Amycolatopsis alba. It exhibits both antibacterial and antifungal properties, primarily functioning by inhibiting protein synthesis in bacteria, which results in their death. Althiomycin has demonstrated effectiveness against a broad spectrum of Gram-positive bacteria, including strains that are resistant to conventional antibiotics. Additionally, it has shown promise in the treatment of multidrug-resistant tuberculosis. Ongoing research into its therapeutic potential and the development of new althiomycin derivatives positions it as a promising candidate for the creation of novel antibiotics to combat the growing issue of antibiotic resistance.

12656-40-5

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12656-40-5 Usage

Uses

Used in Antibacterial Applications:
Althiomycin is used as an antibiotic for treating infections caused by a wide range of Gram-positive bacteria. Its ability to inhibit protein synthesis makes it effective against both antibiotic-sensitive and antibiotic-resistant strains, providing a valuable tool in the fight against bacterial infections.
Used in Antifungal Applications:
Althiomycin also serves as an antifungal agent, offering potential in the treatment of fungal infections. Its dual antibacterial and antifungal properties make it a versatile compound in the medical field.
Used in Multidrug-Resistant Tuberculosis Treatment:
Althiomycin is used as a therapeutic agent for treating multidrug-resistant tuberculosis. Its demonstrated potential in this area highlights its importance in addressing the challenges posed by drug-resistant tuberculosis strains.
Used in Pharmaceutical Research and Development:
Althiomycin is utilized in ongoing research and development efforts to create new derivatives and formulations. These efforts aim to enhance its therapeutic potential, improve its delivery and bioavailability, and expand its applications in treating various infectious diseases, particularly those caused by antibiotic-resistant pathogens.

Check Digit Verification of cas no

The CAS Registry Mumber 12656-40-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,6,5 and 6 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 12656-40:
(7*1)+(6*2)+(5*6)+(4*5)+(3*6)+(2*4)+(1*0)=95
95 % 10 = 5
So 12656-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H17N5O6S2/c1-27-8-2-13(23)21(4-8)16(25)11-7-29-15(20-11)9(5-22)19-14(24)10-6-28-12(18-10)3-17-26/h2-3,6,9,11,18,22H,4-5,7H2,1H3,(H,19,24)/b12-3-

12656-40-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Thiazolecarboxamide, N-[1-[4-[(2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl]-4,5-dihydro-2-thiazolyl]-2-hydroxyethyl]-2-[(hydroxyimino)methyl]-

1.2 Other means of identification

Product number -
Other names Matamycin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:12656-40-5 SDS

12656-40-5Downstream Products

12656-40-5Relevant academic research and scientific papers

TOTAL SYNTHESIS OF ANTIBIOTIC ALTHIOMYCIN

Inami, Kaoru,Shiba, Tetsuo

, p. 2009 - 2012 (2007/10/02)

Antibiotic althiomycin was totally synthesized from D-cysteine via the procedures of the coupling with sodium salt of pyrrolinone, hydroxymethylation, and the coupling with the thiazole part, succesively.

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