37772-89-7

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Pyrrolidinedione is used as an intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and medications.
Used in Agricultural Chemicals:
In the agricultural sector, 2,4-Pyrrolidinedione is employed as a key component in the production of certain agrochemicals, enhancing crop protection and yield.
Used in Electronics Materials:
2,4-Pyrrolidinedione is utilized as a raw material in the manufacturing of electronics materials, playing a role in the development of advanced electronic devices and components.
Used in Petroleum Products:
As an enhancer in petroleum products, 2,4-Pyrrolidinedione helps improve the performance and efficiency of fuels and lubricants.
Used as a Beverage Additive:
2,4-Pyrrolidinedione is also used in the food and beverage industry as an additive, contributing to the taste and quality of certain products.

Upstream product

• 91502-29-3 4-ethoxy-3-pyrrolin-2-one 
• 114473-74-4 6-Aminomethyl-2,2-dimethyl-[1,3]dioxin-4-one 
• 13679-70-4 5-methylthiophene-2-carboxaldehyde 
• 37772-85-3 methyl 4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate 
• 51925-57-6 methyl 2,4-dioxo-3-pyrrolidinecarboxylate 
• 123-91-1 1,4-dioxane 
• 113896-95-0 4-benzyloxy-1,5-dihydropyrrol-2-one 

Downstream Products

• 69778-83-2 4-methoxy-3-pyrrolin-2-one 
• 92233-25-5 2-Methoxy-2-pyrrolin-4-one 
• 12656-40-5 Althiomycin 
• 114343-97-4 2-(1-Propyl-2-oxo-3-pyrrolin-4-yl)amino-3-methylbenzonitrile 
• 433731-24-9 4-((1R,2R)-(2-aminocyclohexyl)amino)-3-pyrrolin-2-one 
• 1613293-50-7 C₂₃H₂₀ClFN₄O₄ 
• 1265206-07-2 5-oxo-2,5-dihydro-1H-pyrrol-3-yl cyclohexanecarboxylate 
• 1265206-05-0 4-(benzoyloxy)-2,5-dihydropyrrol-2(1H)-one 
• 137987-34-9 4-phenylhydrazinoaminopyrroline-2-one 
• 137987-35-0 4-(2-aminophenyl)aminopyrroline-2-one 
• 137987-33-8 4-(phenylamino)-1H-pyrrol-2(5H)-one 

Relevant academic research and scientific papers

A new amide compounds

The invention provides a novel compound (as shown in the formula I) and salt thereof. Experimental results show that the novel compound can be applied to treating and preventing cerebral ischemic diseases and improving sleep; the novel amide compound can generate salt with alkali metal sodium, magnesium, kalium, calcium, organic base tris, diethyl amine, triethylamine and the like and has the functions of treating and preventing ischemic cardiovascular and cerebrovascular diseases and improving sleep.

Studies on the synthesis and bioactivities of 4-amino derivatives of tetramic acid

In order to study the potential bioactivities of 4-amino tetramic acid derivatives, the 4-amination products of pyrrolidine-2,4-diones (5) and 4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrole-3-carboxylates (4) were prepared. The 4-amination of 5 took place in high yield when catalyzed by acetic acid, whereas the 4-amination of 4 was achieved through a 4-ethoxy intermediate, which was prepared by acidic etherification. Their herbicidal, fungicidal, insecticidal, and antitumor activities were tested. The bioassays showed that two of the compounds exhibited good herbicidal activity against dicot Arabidopsis thaliana at a concentration of 10 μg/mL, and one compound gave instinct fungicidal activity against Pythium sp. at a concentration of 2 μg/mL.

REMEDY FOR DIABETES

A method of screening a compound having a hypoglycemic effect (hereinafter referred to as "hypoglycemic compound"), a remedy for diabetes which contains a compound having a novel function mechanism, etc. More specifically speaking, a method of screening a hypoglycemic compound capable of binding to the β subunit of a trimeric GTP-binding protein, a remedy for diabetes comprising a hypoglycemic compound, which is characterized by being capable of binding to the β subunit of a trimeric GTP-binding protein, as the active ingredient, etc.

Tetramic acids as scaffolds: Synthesis, tautomeric and antibacterial behaviour

Efficient synthetic routes for tetramic acids variously substituted on the ring nitrogen, their tautomeric behaviour in solution and their antibiotic activity are reported.

LACTAM COMPOUNDS AND MEDICINAL USE THEREOF

An agent for increasing the sugar-transporting capacity and an agent for preventing and/or treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient.

Dihydronaphthyridine potassium channel openers

Compounds of formula I are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.

Methods of inhibiting the advanced glycosylation of proteins using tetramic and tetronic acids and compositions therefor

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises substituted or unsubstituted tetramic and tetronic acids capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with a carbonyl moiety of an early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.

Inhibitors of the advanced glycosylation of proteins and methods of use therefor

The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, a composition is disclosed which comprises an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with a carbonyl moiety of an early glycosylation product of such target proteins resulting from their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.

3-(heteroarylalkyene)- and 3-(arylalkylene)-2,4(3H,5H)-heterocyclic diones as cancer chemotherapy drugs

Heterocyclic diones of the class containing 3-(heteroarylalkylene)- and 3(arylalkylene)-2, 4 (3H, 5H)-furandiones, and 3-(heteroarylalkylene)-pyrrolidene diones and -thiophene diones are disclosed as being effective cancer chemotherapy drugs, some of whic

Synthesis of tetramic acid

4-Benzyloxy-3-pyrrolin-2-one is a new valuable intermediate product for the production of tetramic acid. Processes are described for the production of such intermediate as well as the production of tetramic acid.