126759-61-3 Usage
Description
1-Acetyl-6-chloro-1H-indole, also known as 6-chloroindol-3-yl acetate, is a chemical compound with the molecular formula C10H8ClNO. It is a derivative of the indole compound and is recognized for its potential biological activities, such as anticancer and antiviral properties. This chemical is a valuable building block for the synthesis of various biologically active molecules and pharmaceutical intermediates, making it a significant component in research and pharmaceutical applications.
Uses
Used in Pharmaceutical Research and Development:
1-Acetyl-6-chloro-1H-indole is used as a key intermediate in the synthesis of biologically active molecules for pharmaceutical applications due to its potential to contribute to the development of new drugs for the treatment of various diseases.
Used in Anticancer Drug Development:
1-Acetyl-6-chloro-1H-indole is used as a potential anticancer agent in the research and development of new treatments for cancer. Its biological activities suggest that it may play a role in modulating oncological signaling pathways, potentially leading to the inhibition of tumor growth and progression.
Used in Antiviral Drug Development:
1-Acetyl-6-chloro-1H-indole is also used as a potential antiviral agent in the research and development of new treatments for viral infections. Its biological properties indicate that it may have the capacity to interfere with viral replication or other processes necessary for the virus to infect host cells.
Used in Synthesis of Biologically Active Molecules:
1-Acetyl-6-chloro-1H-indole is used as a building block in the synthesis of various biologically active molecules, contributing to the advancement of pharmaceutical chemistry and the discovery of new therapeutic agents with diverse applications in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 126759-61-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,7,5 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 126759-61:
(8*1)+(7*2)+(6*6)+(5*7)+(4*5)+(3*9)+(2*6)+(1*1)=153
153 % 10 = 3
So 126759-61-3 is a valid CAS Registry Number.
126759-61-3Relevant articles and documents
Intermolecular dearomative C2-arylation of N-Ac indoles activated by FeCl3
Nandi, Raj Kumar,Ratsch, Friederike,Beaud, Rodolphe,Guillot, Régis,Kouklovsky, Cyrille,Vincent, Guillaume
, p. 5328 - 5331 (2016/04/26)
We report the FeCl3-mediated direct addition of electron-rich arenes to the C2-position of electrophilic N-Ac indoles under mild conditions (room temperature, air). No functional group is required on the arene nucleophile: one of its C-H bonds is added to the C2=C3 double bond of the indole nucleus in a Friedel-Crafts-type reaction. This dearomatisation process delivered a broad range of C2-arylated indolines.
An efficient synthetic method for 2-methoxy-1,2-dihydro-3H-indol-3-ones
Kawasaki, Tomomi,Nonaka, Yoshinori,Matsumura, Ken,Monai, Miyuki,Sakamoto, Masanori
, p. 3251 - 3261 (2007/10/03)
An efficient method for synthesis of 2-methoxy-1,2-dihydro-3H-indol-3- ones using two successive oxidations of indoles is described.
