126781-85-9

Upstream product

• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 4885-02-3 Dichloromethyl methyl ether 
• 206272-38-0 methoxybis(phenylthio)methane 

Downstream Products

• 60380-83-8 trans-4-tert-Butyl-1-(hydroxymethyl)-1-cyclohexanol 
• 54923-65-8 (4-tert-Butylcyclohex-1-enyl)methanol 
• 60380-79-2 cis-4-tert-Butyl-1-(hydroxymethyl)-1-cyclohexanol 
• 343777-27-5 (4-tert-Butyl-cyclohex-1-enyl)-methoxy-methyl-hydroperoxide 
• 74612-02-5 7-tert-Butyl-3-methoxy-1,2-dioxa-spiro[3.5]nonane 
• 74612-02-5 7-tert-Butyl-3-methoxy-1,2-dioxa-spiro[3.5]nonane 
• 59345-43-6 4-tert-Butyl-1-phenylselanyl-cyclohexanecarbaldehyde 
• 169294-55-7 4-tert-butyl-1-methoxy-cyclohexyl hydroperoxide 
• 13004-06-3 cis-(4-tert-butylcyclohexyl)methanol 
• 10601-39-5 trans-(4-tert-butyl-cyclohexyl)-methanol 
• 229323-96-0 1,1-dihydroperoxy-(4-tert-butyl)cyclohexane 
• 40585-98-6 cis-4-t-butylcyclohexane-1-carbaldehyde 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 61187-40-4 4-(tert-butyl)cyclohex-1-enecarbaldehyde 

Relevant academic research and scientific papers

Practical preparation of methyl vinyl ethers through the direct coupling of ketones with CHCl2OMe promoted by Mg/TiCl4/THF

Herein we utilized a new methylene carbenoid as an extremely simple and highly practical reagent for the preparation of vinyl ether with good to excellent yield. This method efficiently effects methoxymethylenation or vinyl ether formation of enolizable, nonenolizable, and sterically hindered ketones. The complexation of Ti–Mg–CHOMe was facilitated, presumably, by THF dramatically increasing the feasibility; and scope of this protocol is to produce vinyl ethers which can be used as convenient building blocks for the preparation of biologically useful molecules.

Saegusa Oxidation of Enol Ethers at Extremely Low Pd-Catalyst Loadings under Ligand-free and Aqueous Conditions: Insight into the Pd(II)/Cu(II)-Catalyst System

A highly efficient and practical Pd(II)/Cu(OAc)2-catalyst system of Saegusa oxidation, which converts enol ethers to the corresponding enals with a number of diverse substrates at extremely low catalyst loadings (500 mol ppm) under ligand-free and aqueous conditions, is described. Its synthetic utility was demonstrated by large-scale applications of the catalyst system to important nature molecules. This work allows Saegusa oxidation to become a highly practical approach to preparing enals and also suggests new insight into the Pd(II)/Cu(II)-catalyst system for dehydrogenation of carbonyl compounds and decreasing Pd-catalyst loadings.

Palladium-catalyzed reactions of enol ethers: Access to enals, furans, and dihydrofurans

The palladium-catalyzed oxidation of alkyl enol ethers to enals, which employs low loadings of a palladium catalyst, is described. The mild oxidation conditions tolerate a diverse array of functional groups, while allowing the formation of di-, tri-, and tetrasubtituted olefins. The application of this methodology to intramolecular reactions of alkyl enol ethers containing pendant alcohols provides furan and 2,5-dihydrofuran products.

New methods for the preparation of 1-alkenyl ethers and sulfides using di- and tri-thioorthoformates

The treatment of carbonyl compounds with the organotitanium species formed from methoxybis(phenylthio)methane and low valent titanium species Cp2Ti[P(OEt)3]2 gave 1-alkenyl ethers in good yields. 1-Alkenyl sulfides were al

Penicillins having a substituted acrylamido side chain

Compounds of formula (I) and their salts and esters: STR1 wherein X is hydrogen or a group NHR1, wherein R1 is hydrogen or an amino protecting group, and R is optionally substituted C5-8 cycloalkyl or cycloalkenyl, are useful in the treatment of bacterial infections.