1268516-11-5

Basic information

• Product Name: (2-(difluoroMethoxy)pyridin-4-yl)Methanol
• Synonyms: (2-(difluoroMethoxy)pyridin-4-yl)Methanol
• CAS NO: 1268516-11-5
• Molecular Formula: C7H7F2NO2
• Molecular Weight: 175.14
• Mol File: 1268516-11-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (2-(difluoroMethoxy)pyridin-4-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-(difluoroMethoxy)pyridin-4-yl)Methanol(1268516-11-5)
• EPA Substance Registry System: (2-(difluoroMethoxy)pyridin-4-yl)Methanol(1268516-11-5)

Safety Data

• Hazardous Substances Data: 1268516-11-5(Hazardous Substances Data)

Usage

General Description

"(2-(difluoroMethoxy)pyridin-4-yl)Methanol" is a chemical compound with the molecular formula C7H7F2NO2. It is a derivative of pyridine with a difluoromethoxy group attached to the 2-position and a hydroxymethyl group attached to the 4-position. (2-(difluoroMethoxy)pyridin-4-yl)Methanol has the potential to be used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique structure and functional groups make it a valuable intermediate for the production of various chemical compounds with potential biological or industrial applications. Additionally, it may also have potential applications in medicinal chemistry due to its structural similarities to biologically active molecules. Further research and exploration of its properties and potential uses are warranted.

Upstream product

• 22282-72-0 2-hydroxyisonicotinic acid 
• 89937-77-9 methyl 2-hydroxypyridine-4-carboxylate 
• 85684-61-3 3-(difluoromethoxy)-benzaldehyde 
• 1895-39-2 sodium chlorodifluoroacetate 
• 188554-13-4 2-hydroxypyridine-4-carboxaldehyde 

Relevant articles and documents

TETRAHYDRONAPHTHYRIDINE DERIVATIVES AS mGluR2-NEGATIVE ALLOSTERIC MODULATORS, COMPOSITIONS, AND THEIR USE

Provided are quinoline carboxamide and quinoline carbonitrile compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R 1, R 2, L, X 1, X 2, and X 3, are as defined herein. The compounds of the invention, and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising them, are useful as non-competitive mGluR2 antagonists, or mGluR2 negative allosteric modulators (NAMs), and may be useful in methods of treating a person in need thereof for diseases or disorders in which the mGluR2-NAM receptor plays a causative role, such as Alzheimer's disease, cognitive impairment, schizophrenia and other mood disorders, pain disorders and sleep disorders.

PYRANYL ARYL METHYL BENZOQUINAZOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS

The present invention is directed to pyranyl aryl methyl benzoquinazolinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as ALzheimer?s disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor