1268520-96-2 Usage
Uses
Used in Pharmaceutical Industry:
4-Amino-2-methylquinazoline-8-carboxylic acid is used as an intermediate in the synthesis of pharmaceuticals for its potential to modify the activity of specific drug targets, contributing to the development of new therapeutic agents.
Used in Agrochemicals:
In the agrochemical industry, 4-Amino-2-methylquinazoline-8-carboxylic acid is utilized as a building block in the synthesis of various agrochemicals, aiding in the development of effective pest control agents.
Used in Organic Pigments:
4-Amino-2-methylquinazoline-8-carboxylic acid is employed as an intermediate in the production of organic pigments, leveraging its chemical properties to create vibrant and stable colorants for various applications.
Used in Dye Production:
4-AMINO-2-METHYLQUINAZOLINE-8-CARBOXYLIC ACID is used as a building block in the production of dyes, where its unique structure contributes to the creation of dyes with specific color characteristics and properties.
Used in Organic Synthesis Research and Development:
4-Amino-2-methylquinazoline-8-carboxylic acid is utilized in organic chemistry research and development as a key component in the synthesis of complex organic molecules, facilitating the discovery and innovation of new chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 1268520-96-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,8,5,2 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1268520-96:
(9*1)+(8*2)+(7*6)+(6*8)+(5*5)+(4*2)+(3*0)+(2*9)+(1*6)=172
172 % 10 = 2
So 1268520-96-2 is a valid CAS Registry Number.
1268520-96-2Relevant academic research and scientific papers
Liu, Kevin K.C.,Huang, Xiaojun,Bagrodia, Shubha,Chen, Jeffrey H.,Greasley, Samantha,Cheng, Hengmiao,Sun, Shaoxian,Knighton, Dan,Rodgers, Caroline,Rafidi, Kristina,Zou, Aihua,Xiao, Jiezhan,Yan, Shengyong
, p. 1270 - 1274 (2011)
Intra-molecular hydrogen bonding was introduced to the quinazoline motif to form a pseudo ring (intra-molecular H-bond scaffold, iMHBS) to mimic our previous published core structures, pyrido[2.3-D]pyrimidin-7-one and pteridinone, as PI3K/mTOR dual inhibitors. This design results in potent PI3K/mTOR dual inhibitors and the purposed intra-molecular hydrogen bonding structure is well supported by co-crystal structure in PI3Kγ enzyme. In addition, a novel synthetic route was developed for these analogs.
