1269800-67-0Relevant academic research and scientific papers
Highly dispersed Ni2P nanoparticles on N,P-codoped carbon for efficient cross-dehydrogenative coupling to access alkynyl thioethers
Song, Tao,Ren, Peng,Xiao, Jianliang,Yuan, Youzhu,Yang, Yong
, p. 651 - 656 (2020)
An ultrafine Ni2P (a metal-rich interstitial phosphide compound) nanoparticles with a narrow size distribution homogeneously dispersed on N,P-codoped carbon was developed for efficient synthesis of alkynyl thioethers via base- and ligand-free cross-dehydrogenative coupling (CDC) of terminal alkynes and thiols using atmospheric air as the oxidant under mild conditions. A remarkable catalytic performance with good functional group compatibility, broad substrate scope and high stability is accomplished. Pyridinic N atoms are identified as basic sites for facilitating the activation of terminal alkynes via hydrogen bonding interactions and play a key role in the success of this base- and ligand-free CDC reaction.
An improved transition-metal-free synthesis of aryl alkynyl sulfides via substitution of a halide at an sp-centre
Chowdhury, Roomi Mohima,Wilden, Jonathan D.
, p. 5859 - 5861 (2015/06/02)
A simple high-yielding preparation of aryl alkynyl sulfides is presented. The reaction of a chloroacetylene with a thiolate salt in the presence of an amine mediator (dimethylamine or N,N′-dimethylethylenediamine) yields the alkynyl sulfides in excellent yields. The alkynyl chloride is easily prepared from the parent alkyne.
Transition-metal-free synthesis of ynol ethers and thioynol ethers via displacement at sp Centers: A revised mechanistic pathway
Gray, Vincent James,Cuthbertson, James,Wilden, Jonathan D.
, p. 5869 - 5874 (2014/07/08)
We present here valuable extensions to our previous work in preparing highly functionalized, heteroatom-substituted alkynes via displacement at an sp center. Our results show that a wide range of ynol ethers can be prepared by the same methodology and that the same protocol can be applied to the synthesis of synthetically useful thioynol ethers. We also present new observations that have led us to revise our original hypothesis in favor of a pathway involving radical intermediates.
