127073-84-1

Basic information

• Product Name: (R)-3-iodo-1-phenyl-1-propanol
• Synonyms: (R)-3-iodo-1-phenyl-1-propanol
• CAS NO: 127073-84-1
• Molecular Weight: 262.09
• Mol File: 127073-84-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (R)-3-iodo-1-phenyl-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-iodo-1-phenyl-1-propanol(127073-84-1)
• EPA Substance Registry System: (R)-3-iodo-1-phenyl-1-propanol(127073-84-1)

Safety Data

• Hazardous Substances Data: 127073-84-1(Hazardous Substances Data)

Usage

General Description

"(R)-3-iodo-1-phenyl-1-propanol" is a compound that is composed of a phenyl group attached to a propanol molecule with an iodine atom at the third position. It is an organic compound and belongs to the class of alcohols. This chemical is often used in organic synthesis as a chiral building block due to its asymmetric carbon center, which gives it stereochemical properties. It can be used in the production of pharmaceuticals, agrochemicals, and various other chemical products. The presence of the iodine atom also makes it a potentially useful tool in radiochemical labeling and related research applications.

Upstream product

• 103548-16-9 (R)-3-phenyl-1,3-dihydroxypropane 
• 936-59-4 3-chloropropiophenone 
• 100306-33-0 (1R)-3-chloro-1-phenylpropanol 

Downstream Products

• 168465-69-8 (R)-α-(2-azidoethyl)benzenemethanol 
• 319924-88-4 (R)-6-methyl-3,4-dihydro-2-phenyl-2H-1-benzopyran 
• 319924-88-4 (S)-6-methyl-3,4-dihydro-2-phenyl-2H-1-benzopyran 
• 1132755-87-3 (R)-3,4-dihydro-2-phenyl-2H-1-benzopyran 
• 157968-59-7 (S)-3,4-dihydro-2-phenyl-2H-1-benzopyran 
• 54910-89-3 (R)-fluoxetine 
• 695229-16-4 C₁₆H₁₄INOS 
• 114247-09-5 (R)-fluoxetine hydrochloride 
• 570384-27-9 [4-(3-amino-1-phenyl-propoxy)-phenyl]-p-tolyl-methanone 
• 138750-31-9 (1R)-3-amino-1-phenyl-1-propanol 
• 155675-18-6 3-Phenyl-propionic acid (R)-3-iodo-1-phenyl-propyl ester 
• 115290-81-8 (R)-N-methyl-3-phenyl-3-hydroxypropylamine 
• 155675-30-2 (R)-3-Benzyloxy-butyric acid (R)-3-iodo-1-phenyl-propyl ester 

Relevant articles and documents

HYDROXY ALIPHATIC SUBSTITUTED PHENYL AMINOALKYL ETHER DERIVATIVES

New hydroxy aliphatic substituted phenyl aminoalkyl ether compounds of formula (I), compositions thereof and their use as a medicament in the treatment of nervous system diseases and/or the treatment of developmental, behavioral and/or mental disorders associated with cognitive deficits.

Copper(ii)-catalyzed enantioselective hydrosilylation of halo-substituted alkyl aryl and heteroaryl ketones: Asymmetric synthesis of (R)-fluoxetine and (S)-duloxetine

A set of reaction conditions has been established to facilitate the non-precious copper-catalyzed enantioselective hydrosilylation of a number of structurally diverse β-, γ- or ε-halo-substituted alkyl aryl ketones and α-, β- or γ-halo-substituted alkyl heteroaryl ketones under air to afford a broad spectrum of halo alcohols in high yields and good to excellent enantioselectivities (up to 99% ee). The developed procedure has been successfully applied to the asymmetric synthesis of antidepressant drugs (R)-fluoxetine and (S)-duloxetine, which highlighted its synthetic utility.

7-PHENYL-ISOQUINOLINE-5-SULFONYLAMINO DERIVATIVES AS INHIBITORS OF AKT (PROTEINKINASE B)

The present invention relates to compounds Formula (I) as inhibitors of AKT activity, which are useful for the treatment of susceptible neoplasms and viral infections.