1271726-25-0

Basic information

• Product Name: N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide
• Synonyms: N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide
• CAS NO: 1271726-25-0
• Molecular Weight: 482.581
• Mol File: 1271726-25-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide(1271726-25-0)
• EPA Substance Registry System: N-{4-[1-(benzenesulfonyl)-1H-indol-2-yl]-4-oxobutyl}benzenesulfonamide(1271726-25-0)

Safety Data

• Hazardous Substances Data: 1271726-25-0(Hazardous Substances Data)

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 40899-71-6 1-benzenesulfonylindole 
• 88000-68-4 1-benzenesulfonyl-pyrrolidin-2-one 

Downstream Products

• 1271726-24-9 2-(E-but-2-en-1-yl)-1,2,3,4,5,7-hexahydro-7-phenylsulfonyl-6H-azocino[4,3-b]indol-6-one 
• 1271726-27-2 4-(N-(E-but-2-en-1-yl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-ol 
• 1271726-29-4 4-(N-(but-2-ynyl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-ol 
• 1271726-31-8 4-(N-(2-iodo-(Z)-but-2-en-1-yl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-ol 
• 1271726-36-3 5-(N-(E-but-2-en-1-yl)phenylsulfonylamido)-2-methyl-2-(1-phenylsulfonylindol-2-yl)pentan-2-ol 
• 1271726-39-6 5-((N-but-2-ynyl)phenylsulfonylamido)-2-methyl-2-(1-phenylsulfonylindol-2-yl)pentan-2-ol 
• 1271726-26-1 4-(N-(E-but-2-en-1-yl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-one 
• 1271726-28-3 4-((N-but-2-ynyl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-one 
• 1271726-30-7 4-(N-(2-iodo-Z-but-2-en-1-yl)phenylsulfonylamido)-1-(1-phenylsulfonylindol-2-yl)butan-1-one 

Relevant articles and documents

Discovery of a novel bicyclic compound, DS54360155, as an orally potent analgesic without mu-opioid receptor agonist activity

We synthesized derivatives of a natural alkaloid, conolidine, and evaluated these derivatives in the acetic acid-induced writhing test and formalin test in ddY mice after oral administration. As a result, we identified (5S)-6-methyl-1,3,4,5,6,8-hexahydro-7H-2,5-methano[1,5]diazonino[7,8-b]indol-7-one sulfate salt, 15a (DS54360155), with a unique and original bicyclic skeleton, as an analgesic more potent than conolidine. Moreover, 15a did not exhibit mu-opioid receptor agonist activity.