88000-68-4Relevant academic research and scientific papers
Synthesis of 1,2,3,4,5,7-hexahydro-6H-azocino[4,3-b]indol-6-ones as intermediates for the synthesis of apparicine
Kettle, Jason G.,Roberts, David,Joule, John A.
experimental part, p. 349 - 370 (2011/04/16)
1-Phenylsulfonylindole is converted in eight steps into 2-(2-iodo-(Z)-but-2-en-1-yl)-6-methyl-1,2,3,4-tetrahydroazocino[4,3-b]indole, previously converted in one step into the indole alkaloid apparicine. The syntheses of other hexahydroazocino[4,3-b]indole potential precursors to the alkaloid are also described. The Japan Institute of Heterocyclic Chemistry.
Treating amnesia with a pyrrolidone derivative
-
, (2008/06/13)
A use of the pyrrolidone derivative represented by the following formula [I] as an anti-amnesitc agent: STR1 wherein R represents a group STR2 X represents --SO2 -- or --CO--; R' represents a hydrogen atom, a lower alkyl group, a trifluoromethy
Approaches to Cytochalasan Synthesis: Preparation and Diels-Alder Reactions of 3-Alkyl- and 3-Acyl-Δ3-pyrrolin-2-ones
Harkin, Shaun A.,Singh, Onkar,Thomas, Eric J.
, p. 1489 - 1499 (2007/10/02)
A series of N-protected Δ3-pyrrolin-2-ones has been prepared, and their Diels-Alder reactivity assessed. 3-Alkyl- and 3-(oximinoalkyl)-1,5-dibenzyl-Δ3-pyrrolin-2-ones were found to isomerize to their 5-benzylidenepyrrolidinone isomer
