1271949-67-7

Basic information

• Product Name: (S)-3-(2-fluoro-5-nitro-phenyl)-3-isothiocyanato-pentan-1-ol
• Synonyms: (S)-3-(2-fluoro-5-nitro-phenyl)-3-isothiocyanato-pentan-1-ol
• CAS NO: 1271949-67-7
• Molecular Weight: 284.311
• Mol File: 1271949-67-7.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-(2-fluoro-5-nitro-phenyl)-3-isothiocyanato-pentan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(2-fluoro-5-nitro-phenyl)-3-isothiocyanato-pentan-1-ol(1271949-67-7)
• EPA Substance Registry System: (S)-3-(2-fluoro-5-nitro-phenyl)-3-isothiocyanato-pentan-1-ol(1271949-67-7)

Safety Data

• Hazardous Substances Data: 1271949-67-7(Hazardous Substances Data)

Upstream product

• 1271949-59-7 (R)-2-methyl-propane-2-sulfinic acid [1-(2-fluoro-5-nitro-phenyl)-prop-(E)-ylidene]-amide 
• 461037-07-0 1-(2-fluoro-5-nitrophenyl)propan-1-one 
• 446-22-0 1-(2-fluorophenyl)propan-1-one 
• 1271949-63-3 (S)-3-amino-3-(2-fluoro-5-nitrophenyl)pentanoic acid 
• 463-71-8 thiophosgene 
• 1271949-65-5 (S)-3-amino-3-(2-fluoro-5-nitro-phenyl)-pentan-1-ol 

Downstream Products

• 1271949-69-9 2-((S)-3-chloro-1-ethyl-1-isothiocyanato-propyl)-1-fluoro-4-nitro-benzene 
• 1271949-71-3 (S)-4-ethyl-4-(2-fluoro-5-nitrophenyl)-5,6-dihydro-4H-[1,3]thiazin-2-ylamine 
• 1271949-73-5 [(S)-4-ethyl-4-(2-fluoro-5-nitro-phenyl)-5,6-dihydro-4H-[1,3]thiazin-2-yl]-carbamic acid tert-butyl ester 
• 1271949-75-7 [(S)-4-(5-amino-2-fluoro-phenyl)-4-ethyl-5,6-dihydro-4H-[1,3]thiazin-2-yl]-carbamic acid tert-butyl ester 
• 1271948-79-8 5-chloro-pyridine-2-carboxylic acid [3-((S)-2-amino-4-ethyl-5,6-dihydro-4H-[1,3]thiazin-4-yl)-4-fluoro-phenyl]-amide formate 

Relevant articles and documents

2 -AMINODIHYDRO [1, 3] THIAZINES AS BACE 2 INHIBITORS FOR THE TREATMENT OF DIABETES

This invention relates to the use of aminodihydrothiazines of the formula wherein R1 to R3 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof, and pharmaceutical compositions con

USE OF AMINODIHYDROTHIAZINES FOR THE TREATMENT OR PREVENTION OF DIABETES

This invention relates to compounds of formula I, wherein R1 to R3 are as defined herein, as well as pharmaceutically acceptable salts thereof, pharmaceutical compositions containing such compounds and methods for using such compound